This paper focuses on the field of automobile passive safety in my country. By scanning the Hybrid III 50th automobile crash dummy, a finite element simulation model of the dummy chest is constructed. The genetic algorithm is used to optimize the parameters. After optimization, all the indicators of the calibration test meet the requirements of the regulations. The simulation results are consistent with the experimental test results, and the error is less than 5%. Then we put the finite element dummy model containing the chest model into the vehicle system for frontal collision simulation analysis. The results show that the score of chest injury is 80%, and the error of the simulation results is less than 10% compared with the test results. The model has a good degree of simulation and can be used for the study of vehicle crash safety performance.