Multi-channel online GC-MS/FID was used to conduct short-term continuous monitoring of volatile organic compounds (VOCs) in the ambient air of industrial parks and urban living quarters in Guangde City, southeast of Anhui Province, China, from April to August 2021. And the concentration change, composition characteristics, contribution to ozone generation potential and main sources of VOCs in the two typical monitoring sites were studied. The results showed that a total of 115 kinds of VOCs were detected in the two monitoring sites during the monitoring period, and the average volume fraction of total VOCs (TVOCs) was (115.13 ± 49.58) × 10^-9 and (132.97 ± 26.66) × 10^-9, respectively. Among the TVOCs detected, the top three species were aromatic hydrocarbons, alkanes and halogenated hydrocarbons. Further analysis of the positive matrix factorization (PMF) model showed that the main sources of VOCs at the two monitoring sites were slightly different. VOCs in the industrial park were mainly from solvent use, industrial emissions, plant emissions, vehicle exhaust, combustion sources, and liquefied petroleum gas (LPG) volatilization, while those in urban living areas mainly came from solvent use, industrial emissions, vehicle exhaust, LPG volatilization, and plant emissions. Specifically, among the VOCs emitted, aromatic hydrocarbons contributed the most to ozone generation potential in both monitoring sites.