With the problem of myopia among teenagers in China showing the trend of younger and heavier myopia, prevention and control of myopia has become an important cause related to national rejuvenation and national development. Improving the effectiveness of myopia prevention and control requires the assistance of science popularization and education, so there is an urgent need for a group of myopia prevention and control talents with professional knowledge of eye health who can carry out popular science propaganda. The establishment of myopia prevention and control publicity group among college students through the three steps of "one foundation, two strengthening and three upgrading" was a means to cultivate high-quality myopia prevention and control talents with popular science propaganda ability.