Based on traditional energy measurement, an integrated acquisition and processing system of laser energy using energy detector, analog digital (AD) acquisition card and signal analysis system is established. Different calculation methods of ouput energy signal by laser interaction with different detectors using Flourier transform is acquired. Different arithmetic is adopted related to different detectors. Energy signal processing software is compiled based on virtual instrument and its processing interface is designed. Synchronous measurement and processing of multi-channel lasers are achieved. The calibration of energy detectors and measurement of laser are accomplished by different energy algorithms for different detectors. Experiments show that the biggest energy error of the measurement system is less than 5% and the repetition of measurement is good, which can satisfy the demand of general detection. The method is handy and credible, which lays the foundation for integration and automation of laser system with energy measurement.