A 100-Gb/s high-speed optical transmitter is proposed and experimentally demonstrated. Based on frequency-quadrupling technique, two sub-channels with a fixed 50-GHz spacing are obtained from one laser source. Using return-to-zero differential quadrature phase-shift keying (RZ-DQPSK) modulation format and polarization multiplexing (PolMux), only low-speed electronic devices of 12.5 GHz are needed for the 100-Gb/s transmitter. This eliminates the need of ultrahigh-speed optoelectronic devices and thus greatly reduces the cost. The experimental results show that this transmitter can achieve good performance in dispersion tolerance of a 25-km single mode fiber (SMF).