Engineering heat transfer is the science that studies the law of heat transfer in engineering applications. It is based on the first and second law of thermodynamics, uses some experimental rules to study the rate of heat transfer, so the experiment part is crucial to this discipline. In order to reinforce students’ understanding of heat transfer process, grasp the core knowledge points of heat transfer theory, the experiment course of heat conduction based on multiple heat transfer modes is set up. This course content includes axial heat conduction experiment, radial heat conduction experiment, fin heat conduction simulation experiment and gas/liquid heat conduction experiment. The application practice shows that the experimental course has rich content and strong comprehensiveness. It effectively improves students’ hands-on skills and project practical ability and achieves good teaching effect.