ObjectiveTo investigate the relationship between coronary collateral circulation status and Adropin level in patients with acute myocardial infarction.MethodsA total of 274 patients with acute myocardial infarction who underwent percutaneous coronary intervention (PCI) at the First Affiliated Hospital of Hebei North University from March, 2023 to April, 2024 were selected as the research object. All patients underwent coronary angiography. According to their coronary collateral circulation status, the patients were divided into a good circulation group (46 cases) and a poor circulation group (228 cases). General data, clinical parameters, and admission Adropin levels of patients from the two groups were compared. Pearson correlation analysis was used to evaluate the association between the coronary collateral circulation status and Adropin levels. Multivariate Logistic regression was applied to analyze the influencing factors of poor coronary collateral circulation.ResultsThe proportion of acute myocardial infarction patients with good coronary collateral circulation prior to PCI was 16.79%. There were statistically significant differences between the good and poor circulation groups in angina pectoris duration, white blood cell count, adrenaline and Adropin level, infarct location, and symptom-to-treatment time (χ²/t/U=8.668, 3.968, 7.392, 7.791, 6.500, 2.666; all P < 0.05). Pearson correlation analysis showed that Rentrop classification was positively correlated with Adropin level (r=0.683, P < 0.05). Multivariate Logistic regression analysis revealed that angina pectoris duration (OR=0.314), symptom-to-treatment time (OR=0.567), white blood cell count (OR=1.278), adrenaline (OR=0.948) and Adropin level (OR=0.902) were influencing factors for coronary collateral circulation status (P < 0.05).ConclusionAcute myocardial infarction patients with good coronary collateral circulation status have higher admission Adropin levels. Adropin level is identified as an influencing factor for the coronary collateral circulation status.