To understand parents’ demand for children’s eye care knowledge during home online classes and to provide basis for targeted health education, the questionnaire of eye care knowledge needs during children’s online course study was conducted among 184 parents of children who visited the ophthalmology department of Children’s Hospital of Fudan University during May 2020. Results showed that 92.0% of the parents wanted to acquire the knowledge of eye care during online lessons, and 73 (39.7%) of the children studied online lessons every day.64 cases (34.8%) had access to video except online course learning. There were 27 cases (14.7%) of online learning time for each online lesson. The daily rest and sleep time of 20 patients (10.9%) were mainly required for eye time control during online lessons, time and methods of rest during home online lessons, etc. Parents have access to health education mainly through the Internet and hospitals.