In order to calibrate line laser human-body 3D scanner quickly and accurately, a multi-sensor synchronous calibration method which uses ceramic gauge block is proposed. V-shaped laser stripe which is made by line laser projection on ceramic gauge block is used as calibration point. 8 CCDs are distributed on 4 uprights, and capture V-shaped light stripe simultaneously to record V-shaped laser stripe pattern. Use gray centroid algorithm and dual fitting line intersection method to extract the light band′s sub-pixel-precision center grid. In order to obtain precision calibration point grid pairs, the grids are paired with 2D translation stage′s world grids. Based on pinhole camera model and using Levenberg-Marquardt (LM) nonlinear optimization algorithm, all sensors′ calibration matrices are obtained. The calibration results are tested by feature points which are different from calibration points, and the result shows that all sensors′ average projection errors are less than 0.3480 mm, standard deviations are less than 0.2524 mm.