In-situ synthesized TiC-Cr7C3-Ti-Ni multiphase metal-ceramics composite coating has been fabricated on Ti-6Al-4V surface by laser cladding in order to improve the comprehensive properties of the material. Composite coating were studied by means of X-ray diffraction (XRD), scanning electron microscope (SEM), energy dispersive spectrometer (EDS), and electron probe microanalyzer (EPMA). Results show that main phase in the coating is β-Ti and γ-Ni solid solution dendrite with eutectic structure of Ti/TiC or Ti/ Cr7C3 distributing in intergranular. Among the crystal structure is β-Ti solid solution which is poor Ni and C, Ti/TiC or Ti/ Cr7C3 distributes in intergranular which is rich Ti and C. The amount of reinforcement phase varies with chemical composition of the coating, the form of crystal in the coating transfers from network to dendrite and equiaxial crystals. The microhardness of the coating increases prominently compares with the matrix.