To avoid the damage of Time Delay and Integration(TDI) CCD sensors in the experimental process, a TDICCD simulation instrument synchronized with input driving clocks is introduced. The simulation instrument is designed with a simple method to meet its physical size in a length of 100 mm and a width of 45 mm. As the size is same as that of a real TDI CCD sensor, the instrument can simulate the photonic characteristics of the pixels for TDI CCD sensors exactly. Furthermore, it can simulate the electrical characteristics of pins in the TDI CCD sensor and can synthesize a complete video output signal, by which an important function, selectable TDI stages with 16,32,48 or 64 stage, is available. Moreover, the instrument can be taken to simulate the thermal delay characteristic between the input driving clock and output OS signals in the temperature adjustable range of 0.5~12.5 ns, which is convenient to the sample time adjustment for the signal circuit.