We propose and design a kind of 650 nm band all organic-inorganic hybrid material embedded Mach-Zehnder (MZ) thermo-optic switch. The main parameters of the thermo-optic switch are optimized, and theoretical transmission simulations of this device are carried out by COMSOL and Rsoft. The material is synthesized in our laboratory. The thermal stability of the material has been greatly improved, since the body of this material is a rigid inorganic backbone of Si-O-Ti chains, and the material has a higher thermo-optic coefficient. By altering the refractive index through changing the Ti cotent in the material, we get the core and clab materials respectively. The material has good film characteristic and workability, which make the production process simple. The device is low loss, and has potential sensing applications. The thermo-optic switch is tested and we get a good near-field output spot. The insertion loss of the device is 6.5 dB, the propagation loss is 0.85 dB/cm, the rise response time is 190 μs and the fall response time is 350 μs, the extinction ratio is 8.5 dB. The thermo-optic switch has broad application prospects in plastic optical fiber transmission system.