Forensic Sciences Research, Volume. 10, Issue 1, owae017(2025)

Beyond Pandora's box: vast potential with significant challenges

Qi Wang*
Author Affiliations
  • Guangzhou Key Laboratory of Forensic Multi-Omics for Precision Identification, School of Forensic Medicine, Southern Medical University, Guangzhou, China
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    Dear editors,

    I recently read the insightful article by Dinis-Oliveira and Azevedo on the prospective role of ChatGPT and similar AI models in forensic science [1]. The article is an important guide to understanding the complex effects of integrating AI into this sensitive area. The authors highlight the great potential benefits of AI in forensic science but also caution about the ethical, legal, and technical challenges involved. I truly appreciate their detailed and thoughtful work on this subject. My considerations are expressed as follows:

    Addressing the phenomenon of AI “Hallucinations” in forensic science: Additionally, it is imperative to address the phenomenon of “hallucinations” or the generation of inaccurate or fictional content by large language models. These AI-driven models, while highly advanced, do not possess true understanding or consciousness, leading to potential errors or fabrications in their outputs [6]. Alarmingly, these inaccuracies can be challenging to detect, even for professionals with relevant expertise. Sometimes, the falsifications are so convincing that they can deceive even established scientists in the field [7]. In forensic applications, where the accuracy of information is paramount, reliance on AI-generated content must be approached with extreme caution. The integration of these models into forensic processes necessitates a framework that not only leverages their capabilities but also incorporates rigorous verification measures by skilled forensic experts. This will ensure that the AI's potential is harnessed effectively while safeguarding against the risks of misinformation, thereby maintaining the integrity and reliability of forensic investigations.

    Moving forward: building a sustainable AI framework in forensic science:

    While the integration of AI in forensic science presents a complex array of challenges, it also offers a path to significant advancements in the field. A cautious yet forward-thinking approach is essential to navigate this journey successfully. We should be enthusiastic about the potential of AI in transforming forensic science and look forward to contributing to this evolving conversation.

    [1] [1] Dinis-OliveiraRJ, AzevedoRMS. ChatGPT in forensic sciences: a new Pandora's box with advantages and challenges to pay attention. Forensic Sci Res. 2023; 8: 275–279.

    [2] [2] Payne-JamesJ, ByardR. Encyclopedia of Forensic and Legal Medicine. London (UK): Academic Press, 2015.

    [4] [4] ChoMK, SankarP. Forensic genetics and ethical, legal and social implications beyond the clinic. Nat Genet. 2004; 36: S8–S12.

    [5] [5] MnookinJL. The uncertain future of forensic science. Daedalus. 2018; 147: 99–118.

    [6] [6] EmsleyR. ChatGPT: these are not hallucinations—they're fabrications and falsifications. Schizophrenia. 2023; 9: 52.

    [7] [7] ElseH. Abstracts written by ChatGPT fool scientists. Nature. 2023; 613: 423.

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    Qi Wang. Beyond Pandora's box: vast potential with significant challenges[J]. Forensic Sciences Research, 2025, 10(1): owae017

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    Paper Information

    Category: Research Articles

    Received: Nov. 25, 2023

    Accepted: Dec. 18, 2023

    Published Online: Sep. 8, 2025

    The Author Email:

    DOI:10.1093/fsr/owae017

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