Nickel-based alloys have many advantages, such as high strength and corrosion resistance, and are widely used in aerospace, energy power and other fields. Laser cladding utilizes a high-energy laser beam to rapidly melt the cladding material on the surface of the base material, forming a good metallurgical bond. Laser cladding of nickel-based alloys has the advantages of high production efficiency and low cost, and has a broad application prospect. In this paper, the current research status is sorted out from the types of nickel-based alloys for laser cladding, the research on laser cladding process parameters and the performance of cladding layer, the current research results are summarized, and the application of nickel-based alloys laser cladding in reactors is prospected, with a view to providing references to the in-depth research and practical application of nickel-based alloys laser cladding.