A new kind of strain measurement Hollow-core Photonic Crystal Fiber (HCPCF) Fabry-Perot (F-P) interferometer sensor is presented. One end of the HCPCF is fused with the single-mode fiber to form the reflecting surface 1. The other end of HCPCF completely collapses to form the reflecting surface 2 by the electrode discharge in the welding machine. So the new F-P interferometer sensor with HCPCF cavity is constituted. The experimental results show that the strain sensitivity of the sensor cavity length of 2 mm at room temperature is 3.1 nm/με, the linearity is 0.999 2 and limit cavity length change is 3 827.3 nm. In the range of 0 ~ 150 ℃, the change of cavity length is about 0.17 μm. Theoretical and experimental results show that the new sensor has a simple fabrication process, high strain sensitivity, low temperature sensitivity and no hysteresis.