The CO2 pulse laser is used in laser spot weld bonding test using Q195 mild steel and adhesive J-11. The fracture process of laser spot weld bonded (LWSB) joints with different spot arrangements is studied. The results show that the adhesive bonded area in LWSB joint firstly fractures, and then the spot fractures, when there is only one spot in LSWB joint. When the spot arrangement in LSWB joint is parallel to the load direction, the fracture sequence is the adhesive bonded area outside of the spot, and the adhesive bonded area inside of the spot. When the spot arrangement in LSWB joint is vertical to the load direction, the adhesive bonded area of the LWSB first fractures, then the adhesive bonded area and the spot fracture together. Besides, the finite element modeling is used to analyze the influence of spot arrangement in LSWB joint on stress distribution under some tensile-shear condition. The calculated results are in good agreement with the experimental results.