Edge-cladding is a key factor in improving saturated small signal gain coefficient of large laser glass. Two kinds of compound, CuO and CuCl, are used as the original materials of Cu2+. The effects of Cu2+ doping content and different original material on glass forming-regions, crystallization stability, physical and chemical properties and absorption coefficient of P2O5-ZnO-Na2O glasses are studied. The results reveal that both CuCl and CuO can enlarge the glass forming-regions and improve the crystallization stability. The absorption coefficient is improved greatly with the content rise of Cu2+, it reaches 59.46 cm-1 at 1053 nm with CuCl mole percent of 6%, and is almost a maximal value.