A semiconductor laser was used to conduct laser transmission welding experiments on polyarylsulfone (PASF) filled with zinc powder absorber and the influence of zinc powder absorber on PASF welding effect and weld morphology was explored with different mass of zinc powder absorber in this paper. Firstly, the shear strength of welded parts was tested and the influence of zinc powder absorbent on the shear strength was analyzed. Secondly, the surface morphology and weld width of welds were observed, and the microstructure of weld pool was observed by scanning electron microscope, and the macroscopic morphology of weld cross section and interface of molten zinc particles were analyzed. The results showed that the zinc powder absorber has a greater impact on the welding of PASF and the best welding effect was got when the zinc powder mass is 16.8 mg. Phenomena such as polymer molecular chain diffusion entanglement, zinc powder particles wrapped by PASF and connected zinc powder particles, in the molten state, have a positive effect on the welding strength.