ObjectiveTo explore the application value of gastric oral contrast-enhanced ultrasound and gastroscopy in early diagnosis of gastric diseases in community hospitals.MethodsPatients with gastric diseases admitted to Pujiang Community Health Service Center from June 2021 to August 2024 were selected. All patients underwent gastroscopy and oral contrast-enhanced ultrasound, with pathological diagnosis as the gold standard. The diagnostic accuracy of gastric oral contrast-enhanced ultrasound, gastroscopy, and combined examination with pathological diagnosis results were evaluated. And the thickness of the gastric wall for benign and malignant gastric diseases was compared.ResultsA total of 268 patients were included. Pathological diagnosis detected 183 positive cases, including 30 malignant cases. There were 151 positive cases detected by gastric oral contrast-enhanced ultrasound, including 22 malignant cases. There were 160 positive cases detected by gastroscopy, including 22 malignant cases; 175 positive cases were detected by joint examination, including 25 malignant cases. The diagnostic accuracy of combined examination for gastritis was 96.91%, which was higher than the 83.51% of gastric oral contrast-enhanced ultrasound (χ²=10.533, P<0.05). The sensitivity of combined examination in diagnosing benign and malignant gastric lesions was 80.00%, which was higher than the 50.00% and 53.00% of gastric oral contrast-enhanced ultrasound and gastroscopy examinations, respectively. The accuracy of the combined examination was 97.39%, which was higher than the 91.79% and 92.54% of gastric oral contrast-enhanced ultrasound and gastroscopy examinations, respectively (χ²=6.826, 8.650; P<0.05). The thickness of the gastric wall in patients with malignant gastric diseases was greater than that in patients with benign gastric diseases (t=20.818, P<0.05).ConclusionThe combined examination of gastric oral contrast-enhanced ultrasound and gastroscopy could improve the detection of gastric diseases and enhance the diagnostic value of benign and malignant gastric diseases, while the thickness of the gastric wall in malignant lesions was greater than that in benign lesions.