For data communication between single wavelength laser communication terminals, good isolation between signal transmission and reception is the key to establishing duplex bidirectional laser communication. In this paper, with respect to the transmission and reception scheme of a single laser wavelength laser communication terminal and its overall communication performance, the influence of the surface roughness and contamination level of key components on the isolation performance of the laser communication terminal is analyzed. The model parameters are derived from Harvey model and ABg model, and the designed scheme is analyzed using TracePro software. When the surface roughness or contamination level of λ/2 wave plate, λ/4 wave plate and optical antenna structure in the signal transmission channel is improved, the backscattering caused by these elements will reduce the isolation performance in the signal transmission channel. At the same time, the measurement result of laser communication terminal isolation is 77.86 dB, which is basically consistent with the software simulation result of 78.35 dB. This can be applied in laser communication system.