Classification of micro-backscattering spectra of liver cancer cell based on PCA and SVM algorithm

Cheng WANG; Jiyi SHI; Gang ZHENG; Huazhong XIANG; Minghui CHEN; Dawei ZHANG

doi:10.3969/j.issn.1005-5630.2020.02.005

Optical Instruments, Volume. 42, Issue 2, 26(2020)

Classification of micro-backscattering spectra of liver cancer cell based on PCA and SVM algorithm

Cheng WANG1... Jiyi SHI1, Gang ZHENG1, Huazhong XIANG1, Minghui CHEN1, and Dawei ZHANG23,* |Show fewer author(s)

Author Affiliations

¹Institute of Biomedical Optics & Optometry, University of Shanghai for Science and Technology, Shanghai 200093, China

²Shanghai Key Laboratory of Modern Optical System, University of Shanghai for Science and Technology, Shanghai 200093, China

³Engineering Research Center of Optical Instruments and Systems，Ministry of Education, University of Shanghai for Science and Technology, Shanghai 200093, China

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Figures & Tables(7)

Fig. 1. The experimental device of fiber confocal back scattering micro-spectrometer

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Fig. 2. Cell pictures under 20× microscope

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Fig. 3. Typical spectra of three kinds of cells

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Fig. 4. Two principal component score of three kinds of cells

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Fig. 5. Prediction results of testing set

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Table 1.
Contribution rate and the cumulative contribution rate of 8 principal components
前8个主成分贡献率及其累积贡献率

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Table 1.
Contribution rate and the cumulative contribution rate of 8 principal components
前8个主成分贡献率及其累积贡献率

主成分	贡献率/%	累积贡献率/%
PC1	79.699 1	79.699 1
PC2	15.775 8	95.444 9
PC3	3.242 5	98.687 4
PC4	0.198 2	98.885 6
PC5	0.128 2	99.013 8
PC6	0.109 7	99.123 5
PC7	0.092 6	99.216 1
PC8	0.085 5	99.301 6

Table 2.
SVM prediction results of samples
SVM预测结果

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Table 2.
SVM prediction results of samples
SVM预测结果

样本序号	实际物体	预测结果	样本序号	实际物体	预测结果
1	MHCC97-L	MHCC97-L	11	HCCLM3	HCCLM3
2	L02	L02	12	HCCLM3	HCCLM3
3	HCCLM3	HCCLM3	13	HCCLM3	HCCLM3
4	MHCC97-L	MHCC97-L	14	HCCLM3	HCCLM3
5	HCCLM3	HCCLM3	15	MHCC97-L	MHCC97-L
6	HCCLM3	HCCLM3	16	L02	L02
7	HCCLM3	HCCLM3	17	HCCLM3	HCCLM3
8	L02	HCCLM3	18	HCCLM3	HCCLM3
9	MHCC97-L	MHCC97-L	19	L02	L02
10	MHCC97-L	MHCC97-L

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Cheng WANG, Jiyi SHI, Gang ZHENG, Huazhong XIANG, Minghui CHEN, Dawei ZHANG. Classification of micro-backscattering spectra of liver cancer cell based on PCA and SVM algorithm[J]. Optical Instruments, 2020, 42(2): 26

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