Laser & Optoelectronics Progress, Volume. 60, Issue 22, 2210005(2023)
Multi-Module Combination Method for Denoising Biological Microscopy Images
Fig. 1. Overall structure of multi-module combined denoising network model
Fig. 2. Structure design of channel association module, adopting different structures in the first and last layers, but the same structure in the middle layers
Fig. 3. Structural design of the multi-scale denoising module, including the information extraction layer of different scale convolution kernels, the middle U-Net layer and the upsampling layer of different magnifications
Fig. 4. Structure of fusion compression module
Fig. 5. Examples of scanned areas of animal and plant samples and their corresponding Ground Truth images. (a) Slice of Cyclops; (b) hair follicle slice; (c) lichen slice; (d) stem longitudinal cut of terminal apex
Fig. 6. Changes of some parameters during network model training and recovery performance at different stages of training. (a) Change trend of loss value of network model in the training set and accuracy in the verification set; (b) recovery effect of a randomly selected image at different stages of network model training
Fig. 7. Visual effect of cross-section image data of bluegrass leaves processed by different denoising methods. (a) Noise image; (b) repair result of Gaussian filter; (c) repair result of BM3D; (d) repair result of DnCNN; (e) repair result of FFDNet; (f) repair result of CBDNet; (g) repair result of DNMMC
Fig. 8. Visual effect of image data of fish gill cross-section samples processed by different denoising methods. (a) Noise image; (b) repair result of Gaussian filter; (c) repair result of BM3D; (d) repair result of DnCNN; (e) repair result of FFDNet; (f) repair result of CBDNet; (g) repair result of DNMMC
Fig. 9. Visual effect of image data of spore cup samples processed by different denoising methods. (a) Noise image; (b) repair result of Gaussian filter; (c) repair result of BM3D; (d) repair result of DnCNN; (e) repair result of FFDNet; (f) repair result of CBDNet; (g) repair result of DNMMC
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Weihua Le, Dingrong Yi, Bocong Zhou, Caihong Huang. Multi-Module Combination Method for Denoising Biological Microscopy Images[J]. Laser & Optoelectronics Progress, 2023, 60(22): 2210005
Category: Image Processing
Received: Apr. 10, 2023
Accepted: Jun. 15, 2023
Published Online: Nov. 6, 2023
The Author Email: Yi Dingrong (yidr@hqu.edu.cn)