Nano-Micro Letters, Volume. 16, Issue 1, 268(2024)

Advances in Polysaccharide-Based Microneedle Systems for the Treatment of Ocular Diseases

Qingdong Bao1...3,4,†, Xiaoting Zhang2,†, Zhankun Hao4, Qinghua Li1,3,4, Fan Wu4, Kaiyuan Wang5, Yang Li2,*, Wenlong Li1,3,4,**, and Hua Gao1,34,*** |Show fewer author(s)
Author Affiliations
  • 1State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao 266071, People’s Republic of China
  • 2State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, People’s Republic of China
  • 3Eye Hospital of Shandong First Medical University, Jinan, 250021, People’s Republic of China
  • 4College of Ophthalmology, Shandong First Medical University, Jinan 250000, People’s Republic of China
  • 5Departments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore 119074, Singapore
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    References(322)

    [16] [16] 1-eye: anatomy, physiology and barriers to drug delivery, in Ocular Transporters and Receptors. ed. by K. Cholkar, S.R. Dasari, D. Pal, and A.K. Mitra (Woodhead Publishing, 2013), pp.1–36

    [28] [28] E.A. Balazs, G. Armand, Glycosaminoglycans and proteoglycans of ocular tissues, in Glycosaminoglycans and Proteoglycans in Physiological and Pathological Processes of Body Systems. ed. by R.V.R.S. Varma, S. Karger (Karger Publishers, Switzerland, 1982), pp.480–499

    [29] [29] A. Tawara, H.H. Varner, J.G. Hollyfield, Distribution and characterization of sulfated proteoglycans in the human trabecular tissue. Invest. Ophthalmol. Vis. Sci. 30, 2215–2231 (1989). PMID: 2793361.

    [32] [32] J.A. Rada, V.R. Achen, S. Penugonda, R.W. Schmidt, B.A. Mount, Proteoglycan composition in the human sclera during growth and aging. Invest. Ophthalmol. Vis. Sci. 41, 1639–1648 (2000). PMID: 10845580.

    [34] [34] J.A. Rada, V.R. Achen, C.A. Perry, P.W. Fox, Proteoglycans in the human sclera. Evidence for the presence of aggrecan. Invest. Ophthalmol. Vis. Sci. 38, 1740–1751 (1997). PMID: 9286262.

    [154] [154] J.Y. Park, Treatment of intraocular lymphoma using biodegradable microneedle implant. 139 (2007). https://europepmc.org/article/ETH/3418

    [280] [280] Y. Zambito, G. Di Colo, Polysaccharides as excipients for ocular topical formulations, Biomaterials Applications for Nanomedicine, (2011), pp. 253–280.

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    Qingdong Bao, Xiaoting Zhang, Zhankun Hao, Qinghua Li, Fan Wu, Kaiyuan Wang, Yang Li, Wenlong Li, Hua Gao. Advances in Polysaccharide-Based Microneedle Systems for the Treatment of Ocular Diseases[J]. Nano-Micro Letters, 2024, 16(1): 268

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    Paper Information

    Category: Research Articles

    Received: May. 6, 2024

    Accepted: Jul. 6, 2024

    Published Online: Jan. 23, 2025

    The Author Email: Li Yang (liyang@xmu.edu.cn), Li Wenlong (wlli@sdfmu.edu.cn), Gao Hua (hgao@sdfmu.edu.cn)

    DOI:10.1007/s40820-024-01477-3

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