Acta Optica Sinica (Online), Volume. 1, Issue 5, 0516001(2024)

Confocal Functional Near-Infrared Spectroscopy Imaging System Using Time-Gated Photon-Counting Technology (Invited)

Zhiyong Li1, Dongyuan Liu1,2、*, and Feng Gao1,2、**
Author Affiliations
  • 1College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
  • 2Tianjin Key Laboratory of Biomedical Detecting Techniques and Instruments, Tianjin 300072, China
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    We introduce a confocal functional near-infrared spectroscopy (fNIRS) imaging system that utilizes a time-gated photon-counting technology. This innovative approach enables the acquisition of high sensitivity and high spatial resolution information within a confocal array while considering cost-effectiveness. The performance of the system is confirmed through a series of functional tests and phantom experiments. Results from these tests show that the system can freely set the position and width of the time gating window within a range of 0 to 10 ns, with a temporal resolution of 10 ps. Phantom experiment results indicate that the system achieves a quantitative ratio improvement of over 32.9% in the confocal array, an enhancement of more than 31.6% in the contrast-to-noise ratio, and an increase of over 29.5% in spatial fidelity. Therefore, the confocal fNIRS imaging system designed in this study, using time-gated photon-counting technology, effectively improves imaging quality at a reasonable cost. This provides instrumental support and methodological reference for related fNIRS research.

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    Zhiyong Li, Dongyuan Liu, Feng Gao. Confocal Functional Near-Infrared Spectroscopy Imaging System Using Time-Gated Photon-Counting Technology (Invited)[J]. Acta Optica Sinica (Online), 2024, 1(5): 0516001

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    Paper Information

    Category: Research Articles

    Received: May. 30, 2024

    Accepted: Jun. 28, 2024

    Published Online: Oct. 8, 2024

    The Author Email: Liu Dongyuan (liudongyuan@tju.edu.cn), Gao Feng (gaofeng@tju.edu.cn)

    DOI:10.3788/AOSOL240428

    CSTR:32394.14.AOSOL240428

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