Laser & Optoelectronics Progress, Volume. 57, Issue 10, 101007(2020)

Joint Segmentation and Registration of Medical Image Based on B-Spline and Level Set Method

Kai Lü* and Jun Wu
Author Affiliations
  • College of Information Engineering, Jiangxi University of Science and Technology, Ganzhou, Jiangxi 341000, China
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    Figures & Tables(11)
    Local refinement diagram of HBS
    Flow chart of algorithm
    Segmentation and registration results of brain MRI and lung CT images. (a) Image to be registered; (b) image of target; (c) initial image difference; (d) segmented contours; (e)-(g) control grid; (h) forward deformed mesh; (i) backward deformed mesh; (j) result of segmentation; (k) result of registration; (l) image difference after registration
    Results of segmentation. (a) Target images without noise-free; (b) images to be registered; (c) segmentation result of images to be registered; (d)-(f) target images with noise intensities of 0.02, 0.05, and 0.1; (g)-(i) segmentation results of Fig. (d)-Fig. (f) by level set method; (j)-(l) segmentation results of Fig. (d)-Fig. (f) by proposed method
    Registration results of two methods. (a) Images to be registered; (b) images of target; (c) registration results of HBS; (d) final image differences of HBS; (e) registration results of DHBS; (f) final image differences of DHBS
    Results of registration. (a) Images to be registered; (b) images of target; (c) registration results of HBS; (d) registration results of joint method; (e) registration results of proposed method; (f) final image differences of HBS; (g) final image differences of joint method; (h) final image differences of proposed method
    Noise experiment comparison chart. (a) Images to be registered; (b) images of target; (c) registration results of joint method; (d) registration results of proposed method; (e) final image differences of joint method; (f) final image differences of proposed method
    • Table 1. DS value of two segmentation methods

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      Table 1. DS value of two segmentation methods

      Noise intensityLevel set methodProposed method
      Triangle /%C-shape /%Triangle /%C-shape /%
      0.0299.3299.2199.3399.36
      0.0596.7695.9999.2799.23
      0.1091.8390.0699.1299.08
    • Table 2. MSE and registration time of two registration methods

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      Table 2. MSE and registration time of two registration methods

      ImageMSERegistration time /s
      HBSDHBSHBSDHBS
      First group35.9833.86762.44799.68
      Second group45.5242.37892.54927.59
      Third group37.5636.15810.26831.63
    • Table 3. MSE and registration time of three registration methods

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      Table 3. MSE and registration time of three registration methods

      ImageMSERegistration time /s
      HBSJoint methodProposed methodHBSJoint methodProposed method
      First group35.9826.8223.97762.44813.56831.26
      Second group45.5235.1731.38892.54939.17960.78
      Third group37.5629.3326.89810.26890.35899.62
      Fourth group72.3152.1651.37997.681105.291123.60
    • Table 4. MSE and registration time under different noise intensities

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      Table 4. MSE and registration time under different noise intensities

      Noise intensityMSERegistration time /s
      Joint methodProposed methodJoint methodProposed method
      026.8223.97813.56831.26
      0.0229.6925.63861.78895.21
      0.0533.5628.29901.33942.45
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    Kai Lü, Jun Wu. Joint Segmentation and Registration of Medical Image Based on B-Spline and Level Set Method[J]. Laser & Optoelectronics Progress, 2020, 57(10): 101007

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    Paper Information

    Category: Image Processing

    Received: Jul. 23, 2019

    Accepted: Oct. 18, 2019

    Published Online: May. 8, 2020

    The Author Email: Lü Kai (1287626767@qq.com)

    DOI:10.3788/LOP57.101007

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