Journal of Radiation Research and Radiation Processing, Volume. 41, Issue 4, 040301(2023)
Effect of CpG-ODN on spleen damage after carbon ion radiation
Fig. 1. Effects of CpG-ODN on spleen index after CIR. the change of spleen index after CIR at the 1st and 3rd day; *p<0.05, compared with CIR control group
Fig. 2. Effects of CpG-ODN on spleen damage after CIR: (a) representative of histological specimens of spleen after CIR at 1st and 3rd day; (b) proportion of white pulp in spleen was quantified; *p<0.05, compared with CIR control group
Fig. 3. Effects of CpG-ODN on DNA DSB and apoptosis of spleen cell after CIR: (a) expression of γ-H2AX protein in spleen was detected by immunohistochemistry after CIR; (b) the number of apoptotic cells in spleen was detected by TUNEL assay after CIR
Fig. 4. Effects of CpG-ODN on CD19+B cells in peripheral blood: (a) the number of CD19+B cells in peripheral blood after CIR at 1st and 3rd day detected by CD19+labeling; (b) the number of CD19+cell quantified; *p<0.05, compared with CIR control group
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Chao ZHANG, Hua FU, Yonghua YI, Jianming CAI, Fu GAO. Effect of CpG-ODN on spleen damage after carbon ion radiation[J]. Journal of Radiation Research and Radiation Processing, 2023, 41(4): 040301
Category: Research Articles
Received: Nov. 10, 2022
Accepted: Feb. 12, 2023
Published Online: Sep. 21, 2023
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