Journal of Innovative Optical Health Sciences, Volume. 16, Issue 5, 2330001(2023)

Photoacoustic microscopy based on transparent piezoelectric ultrasound transducers

Hangbing Peng1... Zhongwen Cheng1, Lvming Zeng1,2,* and Xuanrong Ji1 |Show fewer author(s)
Author Affiliations
  • 1State Key Laboratory of Precision Electronics Manufacturing, Technology and Equipment, Guangdong University of Technology, Guangzhou 510006, China
  • 2Key Lab of Optic-Electronic and Communication, Jiangxi Science and Technology, Normal University Nanchang 330038, China
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    References(80)

    [1] Hand-held optoacoustic imaging: A review. Photoacoustics, 11, 14-27(2018).

    [2] Photoacoustic microscopy. Laser Photon. Rev., 7, 758-778(2013).

    [3] Recent advances in photoacoustic tomography. BME Front., 2021, 1-17(2021).

    [4] Plasmonic nanoparticles with quantitatively controlled bioconjugation for photoacoustic imaging of live cancer cells. Adv. Sci., 3, 1600237(2016).

    [5] Photoacoustic imaging and characterization of the microvasculature. J. Biomed. Opt., 15, 11101(2010).

    [6] In vivo photoacoustic microscopy of human cutaneous microvasculature and a nevus. J. Biomed. Opt., 16, 16015(2011).

    [7] Photoacoustic Imaging of vascular hemodynamics: Validation with blood oxygenation level–dependent MR imaging. Radiology, 275, 110-118(2014).

    [8] In vivo preclinical photoacoustic imaging of tumor vasculature development and therapy. J. Biomed. Opt., 17, 56016(2012).

    [9] Single cell photoacoustic microscopy: A review. IEEE J. Sel. Top. Quant., 22, 137-151(2016).

    [10] Laser-scanning optical-resolution photoacoustic microscopy. Opt. Lett., 34, 1771-1773(2009).

    [11] Real-time four-dimensional optical-resolution photoacoustic microscopy with Au nanoparticle-assisted subdiffraction-limit resolution. Opt. Lett., 36, 1137-1139(2011).

    [12] Portable optical resolution photoacoustic microscopy (pORPAM) for human oral imaging. Opt. Lett., 42, 4434-4437(2017).

    [13] Fast optical-resolution photoacoustic microscopy using a 2-axis water-proofing MEMS scanner. Sci. Rep.-UK, 5, 7932(2015).

    [14] Ultracompact high-resolution photoacoustic microscopy. Opt. Lett., 43, 1615-1618(2018).

    [15] In vivo dark-field reflection-mode photoacoustic microscopy. Opt. Lett., 30, 625-627(2005).

    [16] Reflection-mode optical-resolution photoacoustic microscopy based on a reflective objective. Opt. Exp., 21, 24210(2013).

    [17] Real-time optoacoustic brain microscopy with hybrid optical and acoustic resolution. Laser Phys. Lett., 11, 45601(2014).

    [18] In vivo detection of hemoglobin oxygen saturation and carboxyhemoglobin saturation with multiwavelength photoacoustic microscopy. Opt. Lett., 37, 3414-3416(2012).

    [19] Single-cell label-free photoacoustic flowoxigraphy in vivo. Proc. Natl. Acad. Sci., 110, 5759-5764(2013).

    [20] Intravital imaging of amyloid plaques in a transgenic mouse model using optical-resolution photoacoustic microscopy. Opt. Lett., 34, 3899(2009).

    [21] Second-generation optical-resolution photoacoustic microscopy with improved sensitivity and speed. Opt. Lett., 36, 1134-1136(2011).

    [22] Photoimprint photoacoustic microscopy for three-dimensional label-free subdiffraction imaging. Phys. Rev. Lett., 112, 14302(2014).

    [23] High-speed label-free functional photoacoustic microscopy of mouse brain in action. Nat. Meth., 12, 407-410(2015).

    [24] High-speed widefield photoacoustic microscopy of small-animal hemodynamics. Biomed. Opt. Exp., 9, 4689(2018).

    [25] Hybrid-scanning optical-resolution photoacoustic microscopy for in vivo vasculature imaging. Opt. Lett., 35, 1521-1523(2010).

    [26] Disposable ultrasound-sensing chronic cranial window by soft nanoimprinting lithography. Nat. Commun., 10, 4277(2019).

    [27] Design of efficient, broadband single-element (20–80 MHz) ultrasonic transducers for medical imaging applications. IEEE Trans. Ultrason. Ferroelectr. Freq. Control., 50, 1548-1557(2003).

    [28] Letters: Optically transparent piezoelectric transducer for ultrasonic particle manipulation. IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 61, 389-391(2014).

    [29] Lithium niobate-based transparent ultrasound transducers for photoacoustic imaging. Opt. Lett., 44, 5326(2019).

    [30] Optical-resolution photoacoustic microscopy using transparent ultrasound transducer. Sensors-Basel, 19, 5470(2019).

    [31] Centimeter-scale wide-field-of-view laser-scanning photoacoustic microscopy for subcutaneous microvasculature in vivo. Biomed. Opt. Exp., 12, 2996(2021).

    [32] Transparent high-frequency ultrasonic transducer for photoacoustic microscopy application. IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 67, 1848-1853(2020).

    [33] Transparent ultrasound transducers for multiscale photoacoustic imaging. Proc. SPIE 11642 Photons Plus Ultrasound: Imaging and Sensing 2021, 1164220(2021).

    [34] Piezoelectric single crystal ultrasonic transducers for biomedical applications. Prog. Mater. Sci., 66, 87-111(2014).

    [35] Comparison of PMN–PT transparent ceramics processed by three different sintering methods. J. Mater. Sci. Mater. Electron., 28, 15612-15617(2017).

    [36] Transparent ferroelectric crystals with ultrahigh piezoelectricity. Nature, 577, 350-354(2020).

    [37] A high sensitivity transparent ultrasound transducer based on PMN-PT for ultrasound and photoacoustic imaging. IEEE Sens. Lett., 5, 1-4(2021).

    [38] A photoacoustic finder fully integrated with a solid-state dye laser and transparent ultrasound transducer. Photoacoustics, 23, 100290(2021).

    [39] Design, fabrication, and evaluation of high frequency, single-element transducers incorporating different materials. IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 49, 169-176(2002).

    [40] Transparent ITO coated PVDF transducer for optoacoustic depth profiling. Opt. Commun., 253, 401-406(2005).

    [41] Fully Transparent piezoelectric ultrasonic transducer with 3D printed substrate. 2019 20th Int. Conf. Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII), 234-237(2019).

    [42] Self-made transparent optoacoustic detector for measurement of skin lesion thickness in vivo. Biomed. Phys. Eng. Exp., 8, 35029(2022).

    [43] Single transparent piezoelectric detector for optoacoustic sensing—Design and signal processing. Sensors-Basel, 19, 2195(2019).

    [44] Trimodal system for in vivo skin cancer screening with combined optical coherence tomography-Raman and colocalized optoacoustic measurements. J. Biophoton., 11, e201700288(2018).

    [45] Wearable transparent PVDF transducer for photoacoustic imager in body sensor network. 2020 IEEE Int. Ultrasonics Symp. (IUS), 1-3(2020).

    [46] A focused optically transparent pvdf transducer for photoacoustic microscopy. IEEE Sens. J., 20, 2313-2319(2020).

    [47] Dual-modal photoacoustic and ultrasound microscopy using optically-transparent and high-NA PVDF transducer. Proc. SPIE., 11960, 1196019(2022).

    [48] Photoacoustic imaging with capacitive micromachined ultrasound transducers: Principles and developments. Sensors-Basel, 19, 3617(2019).

    [49] Photoacoustic mammography capable of simultaneously acquiring photoacoustic and ultrasound images. J. Biomed. Opt., 21, 116009(2016).

    [50] A photoacoustic imager with light illumination through an infrared-transparent silicon CMUT array. IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 59, 766-775(2012).

    [51] Backward-mode photoacoustic imaging using illumination through a CMUT with improved transparency. IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 65, 85-94(2018).

    [52] CMUTs on glass with ITO bottom electrodes for improved transparency. 2016 IEEE Int. Ultrasonics Symp. (IUS), 1-4(2016).

    [53] A three-mask process for fabricating vacuum-sealed capacitive micromachined ultrasonic transducers using anodic bonding. IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 62, 972-982(2015).

    [54] A handheld 1D transparent CMUT array probe for photoacoustic imaging: Preliminary results. 2017 IEEE Int. Ultrason. Symp. (IUS), 1-4(2017).

    [55] Transparent capacitive micromachined ultrasonic transducer (CMUT) arrays for real-time photoacoustic applications. Opt. Exp., 28, 13750(2020).

    [56] Transparent capacitive micromachined ultrasonic transducers (CMUTs) for photoacoustic applications. Opt. Exp., 27, 13204(2019).

    [57] Development of a novel transparent flexible capacitive micromachined ultrasonic transducer. Sensors-Basel, 17, 1443(2017).

    [58] A review of transparent sensors for photoacoustic imaging applications. Photonics, 8, 324(2021).

    [59] Optical detection of ultrasound in photoacoustic imaging. IEEE T. Bio.-Med. Eng., 64, 4-15(2017).

    [60] Noise considerations in piezoelectric transparent ultrasound transducers for photoacoustic imaging applications. Proc. SPIE., 11960, 119600S(2022).

    [61] Miniaturized transparent ultrasound sensor for photoacoustic endoscopy. Proc. SPIE., 11960, 1196009(2022).

    [62] Influence of thickness on transparency and sheet resistance of ITO thin films. Eighth Int. Conf. Advanced Semiconductor Devices and Microsystems, 65-68.

    [63] High-speed wide-field photoacoustic microscopy using a cylindrically focused transparent high-frequency ultrasound transducer. Photoacoustics, 28, 100417(2022).

    [64] A transparent ultrasound array for real-time optical, ultrasound, and photoacoustic imaging. BME Front., 2022, 9871098(2022).

    [65] Quadruple ultrasound, photoacoustic, optical coherence, and fluorescence fusion imaging with a transparent ultrasound transducer. Proc. Natl. Acad. Sci., 118, e1920879118(2021).

    [66] Awake mouse brain photoacoustic and optical imaging through a transparent ultrasound cranial window. Opt. Lett., 47, 1121-1124(2022).

    [67] Imaging of cortical oxygen tension and blood flow following targeted photothrombotic stroke. Neurophotonics, 5, 1(2018).

    [68] A miniature multi-contrast microscope for functional imaging in freely behaving animals. Nat. Commun., 10, 99(2019).

    [69] Optical measurement of microvascular oxygenation and blood flow responses in awake mouse cortex during functional activation. J. Cereb. Blood Flow Metab., 42, 510-525(2022).

    [70] Review on practical photoacoustic microscopy. Photoacoustics, 15, 100141(2019).

    [71] Wearable optical resolution photoacoustic microscopy. J. Biophoton., 12, e201900066(2019).

    [72] Photoacoustic computed tomography of human extremities. J. Biomed. Opt., 24, 1(2019).

    [73] In vivo photoacoustic imaging dynamically monitors the structural and functional changes of ischemic stroke at a very early stage. Theranostics, 10, 816-828(2020).

    [74] Photoacoustic microscopy visualizes glioma-induced disruptions of cortical microvascular structure and function. J. Neural Eng., 19, 26027(2022).

    [75] Optically transparent focused transducers for combined photoacoustic and ultrasound microscopy. J. Med. Biol. Eng., 40, 707-718(2020).

    [76] Photoacoustic neuroimaging — Perspectives on a maturing imaging technique and its applications in neuroscience. Front. Neurosci., 15, 655247(2021).

    [77] A skull-removed chronic cranial window for ultrasound and photoacoustic imaging of the rodent brain. Front. Neurosci., 15, 673740(2021).

    [78] Imaging windows for long-term intravital imaging. IntraVital, 3, e29917(2014).

    [79] Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window. Nat. Protoc., 4, 1128-1144(2009).

    [80] Photodynamic therapy for cancer. Nat. Rev. Cancer, 3, 380-387(2003).

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    Hangbing Peng, Zhongwen Cheng, Lvming Zeng, Xuanrong Ji. Photoacoustic microscopy based on transparent piezoelectric ultrasound transducers[J]. Journal of Innovative Optical Health Sciences, 2023, 16(5): 2330001

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    Paper Information

    Category: Research Articles

    Received: Oct. 18, 2022

    Accepted: Dec. 13, 2022

    Published Online: Sep. 26, 2023

    The Author Email: Zeng Lvming (zenglvming@163.com)

    DOI:10.1142/S179354582330001X

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