Optical vortices have demonstrated significant potential in diverse applications, including particle micromanipulation, optical communication, and optical imaging. Among these, the generalized perfect optical vortex (GPOV) has emerged as a focal area of research due to its highly customizable intensity profiles and beam radius that remain independent of topological charges. These attributes have established GPOV as a versatile tool in advanced optical micromanipulation. In this paper, we employ blazed grating technology to enhance the generation of GPOV and integrate them into manipulation experiments involving polystyrene fluorescent microspheres. Through theoretical and experimental validation, we demonstrate the feasibility and precision of transporting particles along customizable paths. This research advances the integration of light field modulation and optical micromanipulation, paving the way for potential applications in microscale delivery systems.