Chinese Journal of Quantum Electronics, Volume. 40, Issue 3, 319(2023)
Research progress of THz-ATR technology for detecting biomedical samples
Fig. 1. Schematic diagram of evanescent wave generated by ATR prism
Fig. 3. (a) Complex dielectric constant of sucrose aqueous solutions with different concentrations [31]; (b) Polarizability of bulk water and hydrated water [31]; (c) THz spectra of nifedipine crystals and mixtures at different concentrations [32]; (d) THz-ATR spectra of nifedipine crystals and nifedipine suspensions with different concentrations [32]
Fig. 5. (a) The ATR amplitude |RP| and phase arg (Rp) of human skin at different times (0, 45, 90 min) after ingesting the glucosesolution [35]; (b) Relationship between THz- ATR spectral reflectance and theophylline concentration at 0.164 THz[36]; (c) THz timedomainwaveform, frequency spectra, dielectric constant and dielectric loss of LCIS culture solution, MCF10A cells and referenceATR prism without samples[37]; (d) The dielectric constant and dielectric loss of MCF10A living cells exposed andunexposed to 10 mmol/L H2O2 after 0, 1, 2 h were compared [37]
Fig. 9. (a) Comparison of the absorption spectra of the glucose pellet, aqueous glucose (0 mg/dL versus 80 mg/dL) and smart hydrogels before and after reaching swelling equilibrium in aqueous glucose (80 mg/dL) [44]; (b) THz absorption coefficient of U87 cells treated with different concentrations of G-Rg3 for 24 hand THz absorption coefficient of U87 cells at a specific frequency [45]
Fig. 10. High-power THz-ATR spectra of α-lactose samples with different concentrations[46, 47]. (a) Time-domain spectra; (b) The corresponding frequency-domain spectra; (c) Characteristic absorption spectra; (d) The change rate of absorption peak position with different concentrations of α-lactose solution
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Haiqing WANG, Wei SHI. Research progress of THz-ATR technology for detecting biomedical samples[J]. Chinese Journal of Quantum Electronics, 2023, 40(3): 319
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Received: Mar. 1, 2023
Accepted: --
Published Online: Jun. 30, 2023
The Author Email: Wei SHI (swshi@mail.xaut.edu.cn)