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Journal of Inorganic Materials, Volume. 39, Issue 1, 90(2024)

pH Responsive Copper-Doped Mesoporous Silica Nanocatalyst for Enhanced Chemo-Chemodynamic Tumor Therapy

Qian HE, Wanlan TANG, Bingkun HAN, Jiayuan WEI, Wenxuan LÜ, and Zhaomin TANG*
Author Affiliations
  • School of New Energy and Materials, Southwest Petroleum University, Chengdu 610500, China
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    Figures & Tables(8)
    Schematic illustration of synthetic procedure and mechanism for enhanced chemo-CDT of nanocatalyst FCDC@Cu-MSN@DA
    1. Schematic illustration of synthetic procedure and mechanism for enhanced chemo-CDT of nanocatalyst FCDC@Cu-MSN@DA

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    Characterization of Cu-MSN and FCDC@Cu-MSN@DA
    2. Characterization of Cu-MSN and FCDC@Cu-MSN@DA

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    pH response of FCDC@Cu-MSN@DA
    3. pH response of FCDC@Cu-MSN@DA

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    ESR signals of FCDC@Cu-MSN@DA for different time (A), ESR spectra of Cu-MSN and FCDC@Cu-MSN@DA (B)
    4. ESR signals of FCDC@Cu-MSN@DA for different time (A), ESR spectra of Cu-MSN and FCDC@Cu-MSN@DA (B)

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    Chemodynamic property of FCDC@Cu-MSN@DA
    5. Chemodynamic property of FCDC@Cu-MSN@DA

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    Laser scanning confocal microscopic images of A549, MCF-7 and 4T1 cancer cells incubated with Cu-MSN@DA and FCDC@Cu-MSN@DA for 5 h
    6. Laser scanning confocal microscopic images of A549, MCF-7 and 4T1 cancer cells incubated with Cu-MSN@DA and FCDC@Cu-MSN@DA for 5 h

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    Fluorescence images of generation of radical oxigen epecies (ROS) by 4T1 cells incubated with different samples
    7. Fluorescence images of generation of radical oxigen epecies (ROS) by 4T1 cells incubated with different samples

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    Effect of chemo-chemodynamic therapy on 4T1 cells by FCDC@Cu-MSN@DA
    8. Effect of chemo-chemodynamic therapy on 4T1 cells by FCDC@Cu-MSN@DA

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    Qian HE, Wanlan TANG, Bingkun HAN, Jiayuan WEI, Wenxuan LÜ, Zhaomin TANG. pH Responsive Copper-Doped Mesoporous Silica Nanocatalyst for Enhanced Chemo-Chemodynamic Tumor Therapy[J]. Journal of Inorganic Materials, 2024, 39(1): 90

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    Paper Information

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    Received: Mar. 23, 2023

    Accepted: --

    Published Online: Mar. 28, 2024

    The Author Email: TANG Zhaomin (tl8687@163.com)

    DOI:10.15541/jim20230151

    Topics

    laser devices and laser physics
    Lasers and Laser Optics
    Laser physics
    laser manufacturing
    Instrumentation, Measurement and Metrology