Journal of Innovative Optical Health Sciences, Volume. 14, Issue 5, 2142004(2021)

Tumor cell death visualization of renal cell carcinoma under the combined effect of the Gratiola officinalis extract and cyclophosphamide using fluorescent staining methods

Artyom Mylnikov1,*... Nikita Navolokin1,2, Dmitry Mudrak1, Natalya Polukonova1, Alla Bucharskaya1,2,3, and Galina Maslyakova12 |Show fewer author(s)
Author Affiliations
  • 1Saratov State Medical University named after V.I. Razumovsky 112 Bolshaya Kazachia Street Saratov 410012, Russia
  • 2National Research Saratov State University 83 Astrakhanskaya Street Saratov 410012, Russia
  • 3National Research Tomsk State University 36 Lenin Avenue Tomsk 634050, Russia
  • show less
    References(21)

    [1] [1] A. A. Neves, K. M. Brindle, "Imaging cell death," J. Nucl. Med. 55(1), 1–4 (2014).

    [2] [2] M. R. Bernsen, K. Kooiman, M. Segbers, F. W. van Leeuwen, M. de Jong, "Biomarkers in preclinical cancer imaging," Eur. J. Nucl. Med. Mol. Imaging 42(4), 579–596 (2015).

    [3] [3] Z. Su, Z. Yang, Y. Xu, Y. Chen, Q. Yu, "Apoptosis, autophagy, necroptosis, and cancer metastasis," Mol. Cancer 14(1), 48 (2015).

    [4] [4] Y. Wu, D. Xing, S. Luo, Y. Tang, Q. Chen, "Detection of caspase-3 activation in single cells by fluorescence resonance energy transfer during photodynamic therapy induced apoptosis," Cancer Lett. 235(2), 239–247 (2006).

    [5] [5] F. Zhou, D. Xing, S. Wu, W. R. Chen, "Intravital imaging of tumor apoptosis with FRET probes during tumor therapy," Mol. Imaging Biol. 12(1), 63–70 (2010).

    [6] [6] Q. Li, F. Q. Ren, C. L. Yang, L. M. Zhou, Y. Y. Liu, J. Xiao, L. Zhu, Z. G. Wang, "Anti-proliferation effects of isorhamnetin on lung cancer cells in vitro and in vivo," Asian Pac. J. Cancer Prev. 16(7), 3035–3042 (2015).

    [7] [7] V. V. Voitkova, "Study of apoptosis with use of flow cytometry," Bull. East Siberian Sci. Center SB RAMS 76(6 Part 1), 220–225 (2010).

    [8] [8] J. S. Ferriss, L. W. Rice, "The role of in vitro directed chemotherapy in epithelial ovarian cancer," Rev. Obstet. Gynecol. 3, 49–54 (2010).

    [9] [9] E. Pastwa, T. Poplawski, U. Lewandowska, S. B. Somiari, J. Blasiak, R. I. Somiari, "Wortmannin potentiates the combined effect of etoposide and cisplatin in human glioma cells," Int. J. Biochem. Cell Biol. 53, 423–431 (2014).

    [10] [10] A. I. Svirnovski, "Leukemia therapy personalization: role of some laboratory technologies," Med. News 9, 6–11 (2013).

    [11] [11] A. V. Polukonova, N. A. Durnova, M. N. Kurchatova, N. A. Navolokin, A. G. Golikov, "The chemical analysis and a method of producing a new from biological active composition of Gratiola Officinalis," Chem. Plant Mater. 4, 165 (2013).

    [12] [12] N. V. Polukonova, N. A. Navolokin, S. V. Raykova, "Anti-inflammatory, antipyretic and antimicrobial activity of the flavanoid-containing extract of Gratiola officinalis," Eksp. Klin. Farmakol. 78(1), 34 (2015).

    [13] [13] N. A. Navolokin, G. N. Maslyakova, N. V. Polukonova, "The expression of apoptosis and autophagy markers in transplantable rat kidney cancer with the administration of flavonoid-containing hedge hyssop (L.) extract," Arch. Pathol. 81(1), 24 (2019).

    [14] [14] A. V. Ulrich, Study of the effect of chokeberry extract on the development of Lewis lung carcinoma and the effectiveness of cyclophosphamide treatment, Proc. Materials of the 15th Scientific Student Conf. Biological Institute, p. 15 (2016).

    [15] [15] A. V. Ulrich, "Rowanberry extract (Sorbus aucuparia) in the complex therapy of experimental tumors," Prospects Dev. Basic Sci. 4, 132–134 (2016).

    [16] [16] N. V. Isaykina, G. I. Kalinkina, T. G. Razina, E. P. Zueva, O. Yu. Rybalkina, A. V. Ulrikh, E. P. Fedorova, A. B. Shilova, "Rowan berries (Sorbus aucuparia L.) as a source of funds for increasing the effectiveness of tumor chemotherapy," Chem. Plant Mater. 4, 165–173 (2017).

    [17] [17] V. Yu. Polyakov, G. I. Kiryanov, V. P. Gerasimenya, A. E. Orlov, E. M. Lazareva, M. I. Murasheva, Yu. S. Chentsov, "Synergism of mycelium extract of fungus Pleurotus ostreatus and medical cytostatics for proliferation and apoptosis of transformed cells," J. "Biol. Membr." 24(5), 379–388 (2007).

    [18] [18] W. F. Benedict, A. Banergjee, N. Vencatesan, "Cyclophosphamide-induced oncogenetic transformation, chromosomal breakage, and sister chromatid exchange following microsomal activation," Cancer Res. 38(9), 2922–2924 (1978).

    [19] [19] M. Tafazoli, P. Van Hummelen, F. Kiefer, M. Kirsch-Volders, "Induction of micronuclei in metabolically competent rat hepatoma cell lines by the promutagens 7,12-dimethylenz[a]anthracene, benzo[a]pyrene and cyclophosphamide," Mutagenesis 10(1), 15–21 (1995).

    [20] [20] A. M. Mylnikov, N. V. Polukonova, D. S. Isaev, A. A. Doroshenko, R. A. Verkhovsky, N. A. Nikolaeva, D. A. Mudrak, N. A. Navolokin, "Identification of the death pathways of human kidney carcinoma A498 cells under the action of Gratiola officinalis extract and green tea flavonoids using fluorescent imaging methods," Opt. Spectrosc. 128(7), 964–971 (2020).

    [21] [21] N. A. Navolokin, N. V. Polukonova, D. A. Mudrak, A. M. Mylnikov, M. A. Baryshnikova, D. A. Khochenkov, A. B. Bucharskaya, A. V. Polukonova, G. N. Maslyakova, "Advantages and possibilities of fluorescent methods for imaging apoptosis and autophagy in human tumor cells in vitro," Opt. Spectrosc. 126(6), 773–780 (2019).

    Tools

    Get Citation

    Copy Citation Text

    Artyom Mylnikov, Nikita Navolokin, Dmitry Mudrak, Natalya Polukonova, Alla Bucharskaya, Galina Maslyakova. Tumor cell death visualization of renal cell carcinoma under the combined effect of the Gratiola officinalis extract and cyclophosphamide using fluorescent staining methods[J]. Journal of Innovative Optical Health Sciences, 2021, 14(5): 2142004

    Download Citation

    EndNote(RIS)BibTexPlain Text
    Save article for my favorites
    Paper Information

    Received: Jan. 19, 2021

    Accepted: May. 11, 2021

    Published Online: Dec. 6, 2021

    The Author Email: Mylnikov Artyom (artyom-mylnikov@mail.ru)

    DOI:10.1142/s1793545821420049

    Topics