[1] [1] A. H. Scott, W. Ralph, "Near-infrared fluorescence: Application to in vivo molecular imaging," Curr. Opin. Chem. Biol. 14, 71-79 (2010).

[2] [2] R. Jianghong, A. Dragulescu-Andrasi, H. Yao, "Fluorescence imaging in vivo: Recent advances," Curr. Opin. Biotechnol. 18, 17-25 (2007).

[3] [3] J. O. Escobedo, O. Rusin, S. Lim R. M. Strongin, "NIR dyes for bioimaging applications," Curr. Opin. Chem. Biol. 14, 64-70 (2010).

[4] [4] Y. Y. Davidson, B. M. Gunn, S. A. Soper, "Spectroscopic and binding properties of near-infrared tricarbocyanine dyes to double-stranded DNA," Appl. Spectrosc. 50, 211-221 (1996).

[5] [5] V. B. Kovalska, K. D. Volkova, M. Y. Losytskyy, O. I. Tolmachev, A. O. Balanda, S. M. Yarmoluk, "6,6'-Disubstituted benzothiazole trimethine cyanines- new fluorescent dyes for DNA detection," Spectrochim. Acta A Molec. Biomol Spectrosc. 65 (2): 271-277 (2006).

[6] [6] S. Luo, E. Zhang, Y. Su, T. Cheng, C. Shi, "A review of NIR dyes in cancer targeting and imaging," Biomaterials 32, 7127-7138 (2011).

[7] [7] T. Ishizawa, N. Fukushima, J. Shibahara,K. Masuda, S. Tamura, T. Aoki et al., "Real-time identification of liver cancers by using indocyanine green fluorescent imaging," Cancer 115, 2491-2504 (2009).

[8] [8] T. Ishizawa, Y. Bandai, N. Harada, A. Muraoka, M. Ijichi, K. Kusaka et al., "Indocyanine green-fluorescent imaging of hepatocellular carcinoma during laparoscopic hepatectomy: An initial experience," Asian J. Endoscop. Surg. 3, 42-45 (2010).

[9] [9] C. Zhang, T. Liu, Y. Su, S. Luo, Y. Zhu, X. Tan, S. Fan, L. Zhang, Y. Zhou, T. Cheng, C. Shi, "A near-infrared fluorescent heptamethine indocyanine dye with preferential tumor accumulation for in vivo imaging," Biomaterials 31, 6612-6617 (2010).

[10] [10] X. Yang, C. Shi, R. Tong, M. Henary et al., "Near infrared heptamethine cyanine dye-mediated cancer imaging," Clin. Cancer Res. 10, 2033-2044 (2010).

[11] [11] X. Tan, S. L. Luo, D. C. Wang, Y. P. Su, T. M. Cheng, C. M. Shi, "A NIR heptamethine dye with intrinsic cancer targeting, imaging and photosensitizing properties," Biomaterials 33, 2230-2239 (2012).

[12] [12] O. A. Andreev, A. D. Dupuy, M. Segala, S. Sandugu, D. A. Serra, C. O. Chichester, Y. K. Reshetnyak, "Mechanism and uses of a peptide that targets tumors an other acidic tissue in vivo," Proc. Natl. Acad. Sci. USA 104, 7893-7898 (2007).

[13] [13] B. G. M. Youssif, K. Okuda, T. Kadonosono, O. I. A. R. Salem, A. A. M. Hayallah, M. A. Hussein et al. "Development of a hypoxia-selective near-infrared fluorescent probe for non-invasive tumor imaging," Chem. Pharm. Bull. 60: 402-407 (2012).

[14] [14] A. Mishra, R. K. Behera, B. K. Mishra, G. B. Behera, "Cyanines during the 1990s: A review," Chem. Rev. 100, 1973-2011 (2000).

[15] [15] A. HocquetM. Langg rd, "An evaluation of theMMt Force Field," J. Molec. Model. 4, 94-112 (1998).

[16] [16] J. J. P. Stewart, "Optimization of parameters for semiempirical methods I. Method," J. Comput. Chem. 10, 209-220 (1989).

[17] [17] J. J. P. Stewart, "Optimization of parameters for semiempirical methods II. Applications," J. Comput. Chem. 10, 221-264 (1989).

[18] [18] M. Ya. Goikhmana, N. P. Yevlampievab, N. V. Kamaninac, I. V. Podeshvoa, I. V. Gofmana, S. A. Mil'tsovd, A. P. Khurchakb, A. V. Yakimanskiia, "New polyamides with main chain cyanine chromophores," Polym. Sci. Ser. A 53, 457-468 (2011).

[19] [19] HyperChem, Version 8.0; Hybercube Inc.: Gainesville, FL, USA (2009).

[20] [20] S. Luciana, T. S. Marcus, O. L. Edeltrudes, S. S. Marcelo, C. A. Maria, R. P. Ivan et al., "Experimental methodologies and evaluations of computer-aided drug design methodologies applied to a series of 2-aminothiophene derivatives with antifungal activities," Molecules 17, 2298-2315 (2012).