Journal of Innovative Optical Health Sciences, Volume. 4, Issue 2, 209(2011)

INTRINSIC FLUORESCENCE CHANGES IN NERVE TERMINALS, EVOKED BY ACTION POTENTIALS, ARE MODULATED BY KREBS CYCLE SUBSTRATES

PAUL KOSTERIN1... ANA LíA OBAID1, and BRIAN M. SALZBERG12,* |Show fewer author(s)
Author Affiliations
  • 1Department of Neuroscience University of Pennsylvania School of Medicine Philadelphia, PA 19104, USA
  • 2Department of Physiology University of Pennsylvania School of Medicine Philadelphia, PA 19104, USA
  • show less
    References(20)

    [1] [1] X. Aubert, B. Chance, R. D. Keynes, "Optical studies of biochemical events in the electric organ of Electrophorus," Proc. R. Soc. B 160, 211-245 (1964).

    [2] [2] B. Chance, "Spectrophotometric and kinetic studies of flavoproteins in tissues, cell suspensions, mitochondria and their fragments," in Flavins and Flavoproteins, E. Slater (ed.), Elsevier Publishing Company, Amsterdam, pp. 496-510 (1966).

    [3] [3] B. Chance, H. Baltscheffsky, "Respiratory enzymes in oxidative phosphorylation. VII. Binding of intramitochondrial reduced pyridine nucleotide," J. Biol. Chem. 233(3), 736-739 (1958).

    [4] [4] B. Chance, M. Baltscheffsky, "Spectroscopic effects of adenosine diphosphate upon the respiratory pigments of rat-heart-muscle sarcosomes," Biochem. J. 68(2), 283-295 (1958).

    [5] [5] B. Chance, P. Cohen, F. J€obsis, B. Schoener, "Intracellular oxidation-reduction states in vivo," Science 137, 499-508 (1962).

    [6] [6] B. Chance, L. Mela, D. Wong, Flavins and Flavoproteins., in 2nd Conference on Flavins and Flavoproteins. Univ. of Tokyo Press, Tokyo (1968).

    [7] [7] B. Chance, G. R. Williams, "Respiratory enzymes in oxidative phosphorylation. II. Difference spectra," J. Biol. Chem. 217(1), 395-407 (1955).

    [8] [8] B. Chance, G. R. Williams, "A method for the localization of sites for oxidative phosphorylation," Nature 176(4475), 250-254 (1955).

    [9] [9] B. Chance, G. R. Williams, "A simple and rapid assay of oxidative phosphorylation," Nature 175(4469), 1120-1121 (1955).

    [10] [10] P. Kosterin, G. H. Kim, M. Muschol, A. L. Obaid, B. M. Salzberg, "Changes in FAD and NADH fluorescence in neurosecretory terminals are triggered by calcium entry and by ADP production," J. Membr. Biol. 208(2), 113-124 (2005).

    [11] [11] K. A. Kasischke, H. D. Vishwasrao, P. J. Fisher, W. R. Zipfel, W. W. Webb, "Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis," Science 305(5680), 99-103 (2004).

    [12] [12] K. C. Reinert, R. L. Dunbar, W. Gao. G. Chen, T. J. Ebner, "Flavoprotein autofluorescence imaging of neuronal activation in the cerebellar cortex in vivo," J. Neurophysiol. 92(1), 199-211 (2004).

    [13] [13] C. W. Shuttleworth, A. M. Brennan, J. A. Connor, "NAD(P)H fluorescence imaging of postsynaptic neuronal activation in murine hippocampal slices," J. Neurosci. 23(8), 3196-3208 (2003).

    [14] [14] K. Shibuki, R. Hishida, H. Murakami, M. Kudoh, T. Kawaguchi, M. Watanabe, S. Watanabe, T. Kouuchi, R. Tanaka, "Dynamic imaging of somatosensory cortical activity in the rat visualized by flavoprotein autofluorescence," J. Physiol. 549 (Pt 3), 919-927 (2003).

    [15] [15] H. Gainer, S. A. Wolfe, Jr., A. L. Obaid, B. M. Salzberg, "Action potentials and frequency-dependent secretion in the mouse neurohypophysis," Neuroendocrinology 43(5), 557-563 (1986).

    [16] [16] M. Muschol, B. M. Salzberg, "Dependence of transient and residual calcium dynamics on actionpotential patterning during neuropeptide secretion," J. Neurosci. 20(18), 6773-6780 (2000).

    [17] [17] A. L. Obaid, R. Flores, B. M. Salzberg, "Calcium channels that are required for secretion from intact nerve terminals of vertebrates are sensitive to omega-conotoxin and relatively insensitive to dihydropyridines. Optical studies with and without voltage-sensitive dyes," J. Gen. Physiol. 93(4), 715-729 (1989).

    [18] [18] T. D. Parsons, A. L. Obaid, B. M. Salzberg, "Aminoglycoside antibiotics block voltage-dependent calcium channels in intact vertebrate nerve terminals," J. Gen. Physiol. 99(4), 491-504 (1992).

    [19] [19] B. M. Salzberg, A. L. Obaid, H. Gainer, "Large and rapid changes in light scattering accompany secretion by nerve terminals in the mammalian neurohypophysis," J. Gen. Physiol. 86(3), 395-411 (1985).

    [20] [20] B. M. Salzberg, A. L. Obaid, D. M. Senseman, H. Gainer, "Optical recording of action potentials from vertebrate nerve terminals using potentiometric probes provides evidence for sodium and calcium components," Nature 306(5938), 36-40 (1983).

    Tools

    Get Citation

    Copy Citation Text

    PAUL KOSTERIN, ANA LíA OBAID, BRIAN M. SALZBERG. INTRINSIC FLUORESCENCE CHANGES IN NERVE TERMINALS, EVOKED BY ACTION POTENTIALS, ARE MODULATED BY KREBS CYCLE SUBSTRATES[J]. Journal of Innovative Optical Health Sciences, 2011, 4(2): 209

    Download Citation

    EndNote(RIS)BibTexPlain Text
    Save article for my favorites
    Paper Information

    Received: --

    Accepted: --

    Published Online: Jan. 10, 2019

    The Author Email: SALZBERG BRIAN M. (bmsalzbe@mail.med.upenn.edu)

    DOI:10.1142/s1793545811001411

    Topics