Quantum dot-sensitized solar cells (QDSC) have attracted extensive attention because of their high efficiency and low-cost potential. In the past five years, the power conversion efficiency (PCE) of QDSC has developed rapidly from less than 10% to more than 15%, showing a promising application prospect. Among them, the design and exploitation of infrared absorption CuInSe2-based quantum dot light-harvesting materials and the significant increase in loading amount promote a rapid promotion for the PCE of QDSC. This review summarized recent work on the design and exploitation of CuInSe2-based QD light-harvesting materials as well as the strategies for high QD uploading.