Spectroscopy and Spectral Analysis, Volume. 41, Issue 12, 3802(2021)

Fluorescence Imaging and Chiral Specific Biological Recognition

Xue-ning FEI*;, Yuan-jie ZHENG, Ying-chun GU, Guang-min LI, Hong-bin ZHAO, and Bao-lian ZHANG
Author Affiliations
  • School of Science, Tianjin Urban Construction University, Tianjin 300384, China
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    Figures & Tables(6)
    Structural differences of folate receptor and pocket relationship of folate binding(a), (b): The figure show the positive and negative sides of folate receptor;(c): The triangle cavity of folate inclusion; (d): The difference of folate α and β subtypes
    Spectrogram of sulfhydryl terminated CdTe nanocrystals
    Circular dichotomous peaks and structures of CdTe quantum dots
    Pyroglutamic acid modified CdSe/ZnS quantum dots
    Chiral space of folate receptor subtypes FRα and FRβ and their interaction with chiral quantum dots
    • Table 1. Molecular structure modification of organic dyes probes

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      Table 1. Molecular structure modification of organic dyes probes

      种类发射波长/nm结构修饰修饰后分子优势
      香豆素类
      (Coumarin)
      <4003、 4位引入吸电子基团, 5~8位引入推电子基团发射波长移至480 nm以上、 量子产率达0.26、 Stokes位移接近100 nm
      花菁类
      (Cyanine dye)
      700~900改变次甲基链的长度荧光波长发生红移、 灵敏度高、 生物相容性好、 化学键合能力强
      氟硼类
      (BODIPY)
      5002、 6位烷基取代修饰大的共轭π键结构芳香环, 增大分子共轭体系发射波长可增至540 nm以上、 量子产率高、 检测灵敏、 吸收峰锐利及荧光带窄及稳定性能高
      罗丹明类
      (Rhodamine B)
      580通过螺环调控氧杂蔥共轭结构与荧光特性检出限低至2 pmol·L-1、 量子产率高、 摩尔消光系数大、 水溶性好
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    Xue-ning FEI, Yuan-jie ZHENG, Ying-chun GU, Guang-min LI, Hong-bin ZHAO, Bao-lian ZHANG. Fluorescence Imaging and Chiral Specific Biological Recognition[J]. Spectroscopy and Spectral Analysis, 2021, 41(12): 3802

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    Paper Information

    Category: Research Articles

    Received: Nov. 21, 2020

    Accepted: --

    Published Online: Dec. 17, 2021

    The Author Email: FEI Xue-ning (xueningfei@126.com)

    DOI:10.3964/j.issn.1000-0593(2021)12-3802-06

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