Laser & Optoelectronics Progress, Volume. 58, Issue 20, 2017001(2021)

Retinal Vessel Segmentation Method Based on Multi-Scale Attention Analytic Network

Wenjie Luo, Guoqing Han*, and Xuedong Tian
Author Affiliations
  • School of Cyber Security and Computer, Hebei University, Baoding, Hebei 071002, China
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    Figures & Tables(18)
    Dilated convolution
    Parallel multi-branch structure
    Attention residual block
    Spatial pyramid pooling module
    Detailed design of segmentation head in booster
    Multi-scale attention analytic network
    Training samples and labels. (a) Training samples; (b) labels
    Image preprocessing. (a) Original image; (b) preprocessed image
    Retinal vessel segmentation results of different algorithms. (a) Original images; (b) labels; (c) results of proposed algorithm; (d) results in Ref. [30]; (e) results in Ref. [17]; (f) results in Ref. [16]; (g) results in Ref. [31]
    Detail comparison of segmentation results. (a) Original images; (b) details of original images; (c) details of labels; (d) segmentation details of proposed algorithm; (e) segmentation details of algorithm in Ref. [30]; (f) segmentation details of proposed algorithm in Ref. [17]
    ROC curves of segmentation results of different algorithms. (a) ROC curves; (b) curves in box of Fig. 11(a)
    PR curves of segmentation results of different algorithms. (a) PR curves; (b) curves in rectangular of Fig. 12(a)
    Changes in various evaluation indicators. (a) F1 value; (b) accuracy; (c) sensitivity; (d) specificity; (e) AUC (ROC); (f) AUC (PR)
    • Table 1. Evaluation metrics for cases not using α values and using different α values

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      Table 1. Evaluation metrics for cases not using α values and using different α values

      αEvaluation Metrics
      F1ASS'AUC (ROC)AUC (PR)
      --0.82670.96690.78680.98700.98580.9157
      0.60.82810.96690.79400.98620.98580.9158
      0.70.83010.96690.80540.98490.98590.9157
      0.80.83210.96690.81820.98350.98570.9152
      0.90.83260.96630.83510.98100.98610.9155
    • Table 2. Average performance evaluation results on CHASEDB1 and STARE

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      Table 2. Average performance evaluation results on CHASEDB1 and STARE

      DatasetMethodF1ASS'AUC (ROC)AUC (PR)
      CHASEDB1SegNet[30]0.80830.96360.76460.98580.98190.8972
      U-Net[17]0.78940.96000.74630.98390.97730.8774
      Attention-UNet[16]0.80250.96240.76190.98470.98010.8898
      FD-UNet[31]0.80970.96360.77280.98480.98300.8991
      MAPNet (ours)0.83260.96630.83510.98100.98610.9155
      STARESegNet[30]0.80520.96390.75980.98700.98230.9082
      U-Net[17]0.79350.96110.74750.98510.97780.8911
      Attention-UNet[16]0.80390.96320.76510.98570.98040.9018
      FD-UNet[31]0.80800.96410.76970.98610.98260.9074
      MAPNet (ours)0.82560.96580.81200.98320.98380.9172
    • Table 3. Comparison of the method proposed on CHASEDB1 with other advanced methods

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      Table 3. Comparison of the method proposed on CHASEDB1 with other advanced methods

      MethodYearF1ASS'AUC
      Method in Ref. [32]2016--0.95810.75070.97930.9716
      Method in Ref. [27]20170.7332--0.72770.97120.9524
      Residual U-Net[33]20180.78000.95530.77260.98200.9779
      Recurrent U-Net[33]20180.78100.96220.74590.98360.9803
      R2U-Net[33]20180.79280.96340.77560.97120.9815
      LadderNet[15]20180.80310.96560.79780.98180.9839
      DEU-Net[13]20190.80370.96610.80740.98210.9812
      Vessel-Net[12]2019--0.96610.81320.98140.9860
      DFA-Net[34]20200.80870.96790.80660.98230.9839
      MAPNet (ours)20200.83260.96630.83510.98100.9861
    • Table 4. Comparison of proposed method with other advanced methods on STARE

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      Table 4. Comparison of proposed method with other advanced methods on STARE

      MethodYearF1ASS'AUC
      Method in Ref. [3]2012--0.95340.75480.97630.9768
      Method in Ref. [32]2016--0.96280.77260.98440.9879
      Method in Ref. [27]20170.7644--0.76800.9738--
      Method in Ref. [35]2019--0.96380.77350.98570.9833
      Method in Ref. [36]2019--0.96400.75230.9885--
      Method in Ref. [10]2020--0.96560.80680.98380.9812
      MAPNet (ours)20200.82560.96580.81200.98320.9838
    • Table 5. Influence of each module on whole model

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      Table 5. Influence of each module on whole model

      ModelF1ASS'AUC (ROC)AUC (PR)
      SubNet_10.81580.96510.77070.98680.98160.9009
      SubNet_20.82000.96570.77830.98660.98320.9054
      SubNet_30.82290.96630.78130.98690.98390.9085
      SubNet_40.82280.96620.78240.98670.98420.9092
      SubNet_50.82530.96660.78540.98690.98460.9106
      SubNet_60.82390.96640.78320.98680.98540.9132
      MAPNet0.83260.96630.83510.98100.98610.9155
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    Wenjie Luo, Guoqing Han, Xuedong Tian. Retinal Vessel Segmentation Method Based on Multi-Scale Attention Analytic Network[J]. Laser & Optoelectronics Progress, 2021, 58(20): 2017001

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    Paper Information

    Category: Medical Optics and Biotechnology

    Received: Dec. 7, 2020

    Accepted: Jan. 11, 2021

    Published Online: Oct. 15, 2021

    The Author Email: Han Guoqing (1655951911@qq.com)

    DOI:10.3788/LOP202158.2017001

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