Journal of Innovative Optical Health Sciences, Volume. 16, Issue 6, 2340004(2023)

The impact of central and obstructive respiratory events on cerebral oxygenation in adults with sleep disordered breathing

Ramin Khatami1...2,3, Dominik Gnaiger1,3, Gordana Hügli1, Ming Qi1, and Zhongxing Zhang12,* |Show fewer author(s)
Author Affiliations
  • 1Center for Sleep Medicine, Sleep Research and Epileptology, Clinic Barmelweid AG, Barmelweid, Switzerland
  • 2Barmelweid Academy, Clinic Barmelweid AG, Barmelweid, Switzerland
  • 3Department of Neurology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
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    References(59)

    [1] C. V. Senaratna, J. L. Perret, C. J. Lodge, A. J. Lowe, B. E. Campbell, M. C. Matheson, G. S. Hamilton, S. C. Dharmage. Prevalence of obstructive sleep apnea in the general population: A systematic review. Sleep Med. Rev., 34, 70-81(2017).

    [2] P. J. J. Strollo, R. M. Rogers. Obstructive sleep apnea. New Engl. J. Med., 334, 99-104(1996).

    [3] D. Yumino, T. D. Bradley. Central sleep apnea and cheyne-stokes respiration. Proc. Am. Thorac. Soc., 5, 226-236(2008).

    [4] D. J. Eckert, A. S. Jordan, P. Merchia, A. Malhotra. Central sleep apnea: Pathophysiology and treatment. Chest, 131, 595-607(2007).

    [5] M. Kohler, J. R. Stradling. Mechanisms of vascular damage in obstructive sleep apnea. Nat. Rev. Cardiol., 7, 677-685(2010).

    [6] H. K. Yaggi, J. Concato, W. N. Kernan, J. H. Lichtman, L. M. Brass, V. Mohsenin. Obstructive sleep apnea as a risk factor for stroke and death. New Engl. J. Med., 353, 2034-2041(2005).

    [7] V. K. Somers. Sleep — a new cardiovascular frontier. N. Engl. J. Med., 353, 2070-2073(2005).

    [8] S. Sharma. Obstructive sleep apnea and coronary artery pathology. Clin. Cardiol., 36, 300-301(2013).

    [9] R. Heinzer, S. Vat, P. Marques-Vidal, H. Marti-Soler, D. Andries, N. Tobback, V. Mooser, M. Preisig, A. Malhotra, G. Waeber, P. Vollenweider, M. Tafti, J. Haba-Rubio. Prevalence of sleep-disordered breathing in the general population: The hypnolaus study. Lancet Respir. Med., 3, 310-318(2015).

    [10] D. J. Durgan, R. M., Bryan. Cerebrovascular consequences of obstructive sleep apnea. J. Am. Heart Assoc., 1, e000091(2012).

    [11] D. Yumino, T. Kasai, D. Kimmerly, V. Amirthalingam, J. S. Floras, T. D. Bradley. Differing effects of obstructive and central sleep apneas on stroke volume in patients with heart failure. Am. J. Respir. Crit. Care Med., 187, 433-438(2013).

    [12] A. Seiler, M. Camilo, L. Korostovtseva, A. G. Haynes, A. K. Brill, T. Horvath, M. Egger, C. L. Bassetti. Prevalence of sleep-disordered breathing after stroke and tia: A meta-analysis. Neurology, 92, e648-e654(2019).

    [13] F. Pizza, M. Biallas, M. Wolf, E. Werth, C. L. Bassetti. Nocturnal cerebral hemodynamics in snorers and in patients with obstructive sleep apnea: A near-infrared spectroscopy study. Sleep, 33, 205-210(2010).

    [14] M. Siebler, A. Nachtmann. Cerebral hemodynamics in obstructive sleep apnea. Chest, 103, 1118-1119(1993).

    [15] M. Furtner, M. Staudacher, B. Frauscher, E. Brandauer, M. M. Esnaola y Rojas, V. Gschliesser, W. Poewe, C. Schmidauer, M. Ritsch-Marte, B. Hogl. Cerebral vasoreactivity decreases overnight in severe obstructive sleep apnea syndrome: A study of cerebral hemodynamics. Sleep Med., 10, 875-881(2009).

    [16] G. Hajak, J. Klingelhofer, M. Schulz-Varszegi, D. Sander, E. Ruther. Sleep apnea syndrome and cerebral hemodynamics. Chest, 110, 670-679(1996).

    [17] Z. Zhang, M. Qi, G. Hügli, R. Khatami. Predictors of changes in cerebral perfusion and oxygenation during obstructive sleep apnea. Sci. Rep., 11, 23510(2021).

    [18] S. Ulrich, Y. Nussbaumer-Ochsner, I. Vasic, E. Hasler, T. D. Latshang, M. Kohler, T. Muehlemann, M. Wolf, K. E. Bloch. Cerebral oxygenation in patients with osa: Effects of hypoxia at altitude and impact of acetazolamide. Chest, 146, 299-308(2014).

    [19] A. Valipour, A. D. McGown, H. Makker, C. O’Sullivan, S. G. Spiro. Some factors affecting cerebral tissue saturation during obstructive sleep apnoea. Eur. Respir. J., 20, 444-450(2002).

    [20] C. O. Olopade, E. Mensah, R. Gupta, D. Huo, D. L. Picchietti, E. Gratton, A. Michalos. Noninvasive determination of brain tissue oxygenation during sleep in obstructive sleep apnea: A near-infrared spectroscopic approach. Sleep, 30, 1747-1755(2007).

    [21] F. Pizza, M. Biallas, U. Kallweit, M. Wolf, C. L. Bassetti. Cerebral hemodynamic changes in stroke during sleep-disordered breathing. Stroke, 43, 1951-1953(2012).

    [22] Z. Zhang, M. Schneider, M. Laures, M. Qi, R. Khatami. The comparisons of cerebral hemodynamics induced by obstructive sleep apnea with arousal and periodic limb movement with arousal: A pilot nirs study. Front Neurosci., 10, 403(2016).

    [23] Z. Zhang, M. Schneider, U. Fritschi, I. Lehner, R. Khatami. Near-infrared spectroscopy (nirs) as a useful tool to evaluate the treatment efficacy of positive airways pressure therapy in patients with obstructive sleep apnea syndrome (osas): A pilot study. J. Innov. Opt. Health Sci., 7, 1450014(2014).

    [24] E. I. Schwarz, M. Furian, C. Schlatzer, J. R. Stradling, M. Kohler, K. E. Bloch. Nocturnal cerebral hypoxia in obstructive sleep apnoea: A randomised controlled trial. Eur. Respir. J., 51, 1800032(2018).

    [25] Z. Zhang, R. Khatami. A biphasic change of regional blood volume in the frontal cortex during non-rapid eye movement sleep: A near-infrared spectroscopy study. Sleep., 38, 1211-1217(2015).

    [26] Z. Zhang, R. Khatami. Predominant endothelial vasomotor activity during human sleep: A near-infrared spectroscopy study. Eur. J. Neurosci., 40, 3396-3404(2014).

    [27] A. Wong, L. Robinson, S. Soroush, A. Suresh, D. Yang, K. Madu, M. N. Harhay, K. Pourrezaei. Assessment of cerebral oxygenation response to hemodialysis using near-infrared spectroscopy (nirs): Challenges and solutions. J. Innov. Opt. Health Sci., 14, 2150016(2021).

    [28] H. Liu, B. Chance, A. H. Hielscher, S. L. Jacques, F. K. Tittel. Influence of blood vessels on the measurement of hemoglobin oxygenation as determined by time-resolved reflectance spectroscopy. Med. Phys., 22, 1209-1217(1995).

    [29] D. Iannetta, E. C. Inglis, R. N. Soares, K. M. McLay, S. Pogliaghi, J. M. Murias. Reliability of microvascular responsiveness measures derived from near-infrared spectroscopy across a variety of ischemic periods in young and older individuals. Microvasc. Res., 122, 117-124(2019).

    [30] G. Pichler, G. Schmolzer, W. Muller, B. Urlesberger. Body position-dependent changes in cerebral hemodynamics during apnea in preterm infants. Brain Dev., 23, 395-400(2001).

    [31] R. S. C. Horne, S. Sun, S. R. Yiallourou, K. L. Fyfe, A. Odoi, F. Y. Wong. Comparison of the longitudinal effects of persistent periodic breathing and apnoea on cerebral oxygenation in term- and preterm-born infants. J. Physiol., 596, 6021-6031(2018).

    [32] O. G. Jenni, M. Wolf, M. Hengartner, K. Siebenthal, M. Keel, H. U. Bucher. Impact of central, obstructive and mixed apnea on cerebral hemodynamics in preterm infants. Biol. Neonate., 70, 91-100(1996).

    [33] P. F. Decima, K. L. Fyfe, A. Odoi, F. Y. Wong, R. S. Horne. The longitudinal effects of persistent periodic breathing on cerebral oxygenation in preterm infants. Sleep Med., 16, 729-735(2015).

    [34] L. Tabone, S. Khirani, Arroyo J. Olmo, A. Amaddeo, A. Sabil, B. Fauroux. Cerebral oxygenation during respiratory events in children with sleep-disordered breathing and associated disorders. J. Pediatr., 214, 134-140(2019).

    [35] K. Tamanyan, A. Weichard, S. N. Biggs, M. J. Davey, G. M. Nixon, L. M. Walter, R. S. C. Horne. The impact of central and obstructive respiratory events on cerebral oxygenation in children with sleep disordered breathing. Sleep, 42, zsz044(2019).

    [36] Z. Zhang, N. Bolz, M. Laures, M. Oremek, C. Schmidt, M. Qi, R. Khatami. Cerebral blood volume and oxygen supply uniformly increase following various intrathoracic pressure strains. Sci. Rep., 7, 8344(2017).

    [37] R. B. Berry, R. Brooks, C. E. Gamaldo, S. M. Harding, R. M. Lloyd, C. L. Marcus, B. V. Vaughn. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications(2017).

    [38] S. Fantini, M.-A. Franceschini, J. S. Maier, S. A. Walker, B. B. Barbieri, E. Gratton. Frequency-domain multichannel optical detector for noninvasive tissue spectroscopy and oximetry. OPTICE, 34, 32-42(1995).

    [39] S. Fantini, A. Sassaroli. Frequency-domain techniques for cerebral and functional near-infrared spectroscopy. Front Neurosci., 14, 300(2020).

    [40] M. A. Franceschini, S. Thaker, G. Themelis, K. K. Krishnamoorthy, H. Bortfeld, S. G. Diamond, D. A. Boas, K. Arvin, P. E. Grant. Assessment of infant brain development with frequency-domain near-infrared spectroscopy. Pediatr. Res., 61, 546-551(2007).

    [41] Z. Zhang, M. Qi, G. Hugli, R. Khatami. The challenges and pitfalls of detecting sleep hypopnea using a wearable optical sensor: Comparative study. J. Med. Internet Res., 23, e24171(2021).

    [42] Z. Zhang, M. Qi, G. Hügli, R. Khatami. Quantitative changes in muscular and capillary oxygen desaturation measured by optical sensors during continuous positive airway pressure titration for obstructive sleep apnea. Biosensors, 12, 3(2021).

    [43] V. Quaresima, S. Sacco, R. Totaro, M. Ferrari. Noninvasive measurement of cerebral hemoglobin oxygen saturation using two near infrared spectroscopy approaches. J. Biomed. Opt., 5, 201-205(2000).

    [44] T. W. Scheeren, P. Schober, L. A. Schwarte. Monitoring tissue oxygenation by near infrared spectroscopy (nirs): Background and current applications. J. Clin. Monit. Comput., 26, 279-287(2012).

    [45] Z. Zhang, R. Khatami. Predominant endothelial vasomotor activity during human sleep: A near-infrared spectroscopy study. Eur. J. Neurosci., 40, 3396-3404(2014).

    [46] W. S. Cleveland, S. J. Devlin. Locally weighted regression — an approach to regression-analysis by local fitting. J. Am. Stat. Assoc., 83, 596-610(1988).

    [47] K. M. McLay, J. P. Nederveen, S. Pogliaghi, D. H. Paterson, J. M. Murias. Repeatability of vascular responsiveness measures derived from near-infrared spectroscopy. Physiol. Rep., 4, e12772(2016).

    [48] S. Nakagawa, H. Schielzeth. A general and simple method for obtaining r2 from generalized linear mixed-effects models. Meth. Ecol. Evol., 4, 133-142(2013).

    [49] R. Xu. Measuring explained variation in linear mixed effects models. Stat. Med., 22, 3527-3541(2003).

    [50] C. W. Zwillich. Sleep apnoea and autonomic function. Thorax, 53, S20-S24(1998).

    [51] K. Yaffe, A. M. Laffan, S. L. Harrison, S. Redline, A. P. Spira, K. E. Ensrud, S. Ancoli-Israel, K. L. Stone. Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women. JAMA, 306, 613-619(2011).

    [52] N. A. Marchi, G. Solelhac, M. Berger, J. Haba-Rubio, N. Gosselin, P. Vollenweider, P. Marques-Vidal, J. Popp, A. von Gunten, M. Preisig, B. Draganski, R. Heinzer. Obstructive sleep apnoea and 5-year cognitive decline in the elderly. Eur. Respir. J., 61, 2201621(2023).

    [53] A. G. Andrade, O. M. Bubu, A. W. Varga, R. S. Osorio. The relationship between obstructive sleep apnea and alzheimer’s disease. J. Alzheimers Dis., 64, S255-S270(2018).

    [54] B. A. Edwards, A. Malhotra, S. A. Sands. Adapting our approach to treatment-emergent central sleep apnea. Sleep, 36, 1121-1122(2013).

    [55] L. J. Findley, S. C. Wilhoit, P. M. Suratt. Apnea duration and hypoxemia during rem sleep in patients with obstructive sleep apnea. Chest, 87, 432-436(1985).

    [56] J. P. Janssens, T. Rochat, E. Sforza. Rapid eye movement-related disordered breathing: Clinical and polysomnographic features. Chest, 128, 3350-3357(2005).

    [57] B. Mokhlesi, L. A. Finn, E. W. Hagen, T. Young, K. M. Hla, E. Van Cauter, P. E. Peppard. Obstructive sleep apnea during rem sleep and hypertension. Results of the wisconsin sleep cohort. Am. J. Respir. Crit. Care. Med., 190, 1158-1167(2014).

    [58] S. Javaheri, D. M. Rapoport, A. R. Schwartz. Distinguishing central from obstructive hypopneas on a clinical polysomnogram. J. Clin. Sleep Med., 19, 823-834(2023).

    [59] A. Xie, J. B. Skatrud, R. Khayat, J. A. Dempsey, B. Morgan, D. Russell. Cerebrovascular response to carbon dioxide in patients with congestive heart failure. Am. J. Respir. Crit. Care. Med., 172, 371-378(2005).

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    Ramin Khatami, Dominik Gnaiger, Gordana Hügli, Ming Qi, Zhongxing Zhang. The impact of central and obstructive respiratory events on cerebral oxygenation in adults with sleep disordered breathing[J]. Journal of Innovative Optical Health Sciences, 2023, 16(6): 2340004

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    Paper Information

    Category: Research Articles

    Received: Dec. 31, 2022

    Accepted: Jun. 6, 2023

    Published Online: Dec. 23, 2023

    The Author Email: Zhang Zhongxing (zhongxing.zhang@barmelweid.ch)

    DOI:10.1142/S1793545823400047

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