Acta Optica Sinica, Volume. 40, Issue 4, 0411002(2020)

Three-Dimensional Imaging of Tumor Tissues Based on Photothermal Optical Coherence Tomography

Bo Wei1, Zhiling Yuan1, and Zhilie Tang1,2、*
Author Affiliations
  • 1School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou, Guangdong 510006, China
  • 2National Experimental Teaching Demonstration Center of Basic Course of Physics, South China Normal University, Guangzhou, Guangdong 510006, China
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    Figures & Tables(7)
    Experimental setup of PT-OCT
    Experimental results of imaging phantom. (a) Raw tomogram of OCT; (b) tomogram of PT-OCT obtained by phase difference algorithm; (c) tomogram of PT-OCT obtained by average amplitude algorithm; (d)-(f) gray-level curves corresponding to dashed lines in Fig. 2(a)-(c)
    Experimental results of imaging mouse ear. (a) Three-dimensional image of OCT; (b) three-dimensional top view of OCT; (c) three-dimensional top view of PT-OCT obtained by phase difference algorithm; (d) three-dimensional top view of PT-OCT obtained by average amplitude algorithm
    Tomograms of mouse ear. (a) Raw tomogram of OCT; (b) tomogram of PT-OCT obtained by phase difference algorithm; (c) tomogram of PT-OCT obtained by average amplitude algorithm; (d)-(f) average values of gray values corresponding to same position in middle of Fig. 4(a)-(c)
    Photograph of actual sample using in experiment
    PT-OCT images of tumor site. (a) Three-dimensional image of PT-OCT; (b) top view of PT-OCT; (c) side view of PT-OCT marked with pseudo-color photothermal signal; (d) three-dimensional image of PT-OCT marked with pseudo-color photothermal signal
    Specific-depth images of tumor site. (a) Top view of PT-OCT of tumor site; (b)-(i) sectional views at 0.5, 1, 1.5, 2, 2.5, 3, 3.5, and 4 mm from top surface of tumor, respectively
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    Bo Wei, Zhiling Yuan, Zhilie Tang. Three-Dimensional Imaging of Tumor Tissues Based on Photothermal Optical Coherence Tomography[J]. Acta Optica Sinica, 2020, 40(4): 0411002

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    Paper Information

    Category: Imaging Systems

    Received: Jul. 23, 2019

    Accepted: Oct. 21, 2019

    Published Online: Feb. 11, 2020

    The Author Email: Tang Zhilie (tangzhl@scnu.edu.cn)

    DOI:10.3788/AOS202040.0411002

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