Laser & Optoelectronics Progress, Volume. 55, Issue 3, 030009(2018)

Blood Glucose Noninvasive Measurement Based on Photoacoustic Technique

Yu Ding, Qingkai Yao, Lijun Deng, Zhong Ren, Zhen Huang, Lüming Zeng*, and Guodong Liu
Author Affiliations
  • Key Laboratory of Optics-Electronics and Communication, Jiangxi Science and Technology Normal University, Nanchang, Jiangxi 330038, China
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    Figures & Tables(7)
    (a) Block diagram of the blood glucose photoacoustic measurement system used by Kinnunen's group; (b) relationship between the blood glucose photoacoustic value and the concentration in pig whole blood at wavelength of 1064 nm; (c) relationship between the blood glucose photoacoustic value and the concentration in pig whole blood at wavelength of 532 nm
    (a) Photoacoustic blood glucose determination system designed by Zhao's group; (b) experiment result of the glucose concentration from 0 to 100 mg/dL; (c) ultrasonic velocity versus temperature at different solution concentrations
    (a) Schematic of our research group's photoacoustic noninvasive detection unit; (b) time-resolved photoacoustic signal of glucose solutions with different mass concentrations; (c) predicted mass concentration of glucose solutions at characteristic wavelengths of 1410 nm and 1510 nm
    (a) Diagram of the photoacoustic blood glucose detection apparatus used by Zhao's group; (b) relative photoacoustic change of glucose solution with different concentrations; (c) relationship between photoacoustic signal change and glucose mass concentration in the fresh blood sample
    (a) Block diagram of experimental setup used by Pai's group; (b) Clarke error grid analysis plot showing a comparison of predicted blood glucose values and reference values from 30 subjects
    (a) Schematic of blood glucose photoacoustic noninvasive detection system used by Kottmann's group; (b) photoacoustic signal dependence on glucose concentration between 0 and 2000 mg/dL; (c) photoacoustic spectra of a human epidermal skin sample in contact with water, 2 g/dL and 10 g/dL glucose solutions; (d) schematic diagram of the fiber-coupled photoacoustic cell; (e) photoacoustic spectra of human skin measured at the finger tip and the forearm
    (a) Schematic of the photoacoustic measurement system of skin glucose used by Pleitez's group[25]; (b) diagram showing the photoacoustic cell for human skin blood glucose photoacoustic measurement; (c) photoacoustic spectra of a diabetic volunteer as a result of the variation of blood glucose concentrations; (d) Clarke error grid between measured blood glucose and predicted blood glucose
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    Yu Ding, Qingkai Yao, Lijun Deng, Zhong Ren, Zhen Huang, Lüming Zeng, Guodong Liu. Blood Glucose Noninvasive Measurement Based on Photoacoustic Technique[J]. Laser & Optoelectronics Progress, 2018, 55(3): 030009

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    Paper Information

    Category: General

    Received: Aug. 16, 2017

    Accepted: --

    Published Online: Sep. 10, 2018

    The Author Email: Zeng Lüming ( zenglvming@163.com)

    DOI:10.3788/LOP55.030009

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