[3] [3] SI L, WINZENBERG T M, JIANG Q, et al. Projection of osteoporosis-related fractures and costs in China: 2010-2050[J]. Osteoporos Int, 2015, 26(7): 1929-1937.

[4] [4] WANG X H, AO Q, TIAN X H, et al. 3D bioprinting technologies for hard tissue and organ engineering[J]. Materials, 2016, 9(10): 802.

[5] [5] MARIN E, BOSCHETTO F, PEZZOTTI G. Biomaterials and biocompatibility: An historical overview[J]. J Biomed Mater Res A, 2020, 108(8): 1617-1633.

[6] [6] HENCH L L, SPLINTER R J, ALLEN W C, et al. Bonding mechanisms at the interface of ceramic prosthetic materials[J]. J Biomed Mater Res, 1971, 5(6): 117-141.

[8] [8] FU H L, FU Q, ZHOU N, et al. In vitro evaluation of borate-based bioactive glass scaffolds prepared by a polymer foam replication method[J]. Mater Sci Eng C, 2009, 29(7): 2275-2281.

[9] [9] MARION N W, LIANG W, LIANG W, et al. Borate glass supports the in vitro osteogenic differentiation of human mesenchymal stem cells[J]. Mech Adv Mater Struct, 2005, 12(3): 239-246.

[10] [10] LI S J, ZHANG L Y, LIU C Y, et al. Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects[J]. Bioact Mater, 2023, 23: 101-117.

[11] [11] HUANG W H, LI Y D, RAHAMAN M, et al. Mechanisms for converting bioactive silicate, borate, and borosilicate glasses to hydroxyapatite in dilute phosphate solution[J]. Phys Chem Glasses Eur J Glass Sci Technol Part B, 2006, 47: 647-658.

[12] [12] ZHANG W, ZHAO F J, HUANG D Q, et al. Strontium-substituted submicrometer bioactive glasses modulate macrophage responses for improved bone regeneration[J]. ACS Appl Mater Interfaces, 2016, 8(45): 30747-30758.

[13] [13] DECKER S, ARANGO-OSPINA M, REHDER F, et al. In vitro and in ovo impact of the ionic dissolution products of boron-doped bioactive silicate glasses on cell viability, osteogenesis and angiogenesis[J]. Sci Rep, 2022, 12: 8510.

[14] [14] BROWN R F, RAHAMAN M N, DWILEWICZ A B, et al. Effect of borate glass composition on its conversion to hydroxyapatite and on the proliferation of MC3T3-E1 cells[J]. J Biomed Mater Res A, 2009, 88(2): 392-400.

[15] [15] AN J, YANG H, ZHANG Q, et al. Natural products for treatment of osteoporosis: The effects and mechanisms on promoting osteoblast-mediated bone formation[J]. Life Sci, 2016, 147: 46-58.

[16] [16] PANG L B, TIAN P F, CUI X, et al. In situ photo-cross-linking hydrogel accelerates diabetic wound healing through restored hypoxia- inducible factor 1-alpha pathway and regulated inflammation[J]. ACS Appl Mater Interfaces, 2021, 13(25): 29363-29379.

[17] [17] LIN C Y, SONG X, SEAMAN K, et al. Microfluidic co-culture platforms for studying osteocyte regulation of other cell types under dynamic mechanical stimulation[J]. Curr Osteoporos Rep, 2022, 20(6): 478-492.

[18] [18] WADMAN M. FDA no longer has to require animal testing for new drugs[J]. Science, 2023, 379(6628): 127-128.