Journal of Innovative Optical Health Sciences, Volume. 18, Issue 1, 2550002(2025)

Neural-field-based image reconstruction for bioluminescence tomography

Xuanxuan Zhang1, Xu Cao2, Jiulou Zhang3, Lin Zhang4, and Guanglei Zhang5、*
Author Affiliations
  • 1School of Communications and Information Engineering & School of Artificial Intelligence, Xi’an University of Posts and Telecommunications, Xi’an, Shaanxi 710121, P. R. China
  • 2Engineering Research Center of Molecular and Neuro Imaging of the Ministry of Education & School of Life Science and Technology, Xidian University, Xi’an, Shaanxi 710071, P. R. China
  • 3Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P. R. China
  • 4School of Information Science and Engineering, Shandong Normal University, Jinan, Shandong 250014, P. R. China
  • 5School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, P. R. China
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    Deep learning (DL)-based image reconstruction methods have garnered increasing interest in the last few years. Numerous studies demonstrate that DL-based reconstruction methods function admirably in optical tomographic imaging techniques, such as bioluminescence tomography (BLT). Nevertheless, nearly every existing DL-based method utilizes an explicit neural representation for the reconstruction problem, which either consumes much memory space or requires various complicated computations. In this paper, we present a neural field (NF)-based image reconstruction scheme for BLT that uses an implicit neural representation. The proposed NF-based method establishes a transformation between the coordinate of an arbitrary spatial point and the source value of the point with a relatively light-weight multilayer perceptron, which has remarkable computational efficiency. Another simple neural network composed of two fully connected layers and a 1D convolutional layer is used to generate the neural features. Results of simulations and experiments show that the proposed NF-based method has similar performance to the photon density complement network and the two-stage network, while consuming fewer floating point operations with fewer model parameters.

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    Xuanxuan Zhang, Xu Cao, Jiulou Zhang, Lin Zhang, Guanglei Zhang. Neural-field-based image reconstruction for bioluminescence tomography[J]. Journal of Innovative Optical Health Sciences, 2025, 18(1): 2550002

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    Paper Information

    Category: Research Articles

    Received: Aug. 22, 2024

    Accepted: Oct. 10, 2024

    Published Online: Feb. 21, 2025

    The Author Email: Zhang Guanglei (guangleizhang@buaa.edu.cn)

    DOI:10.1142/S1793545825500026

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