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High Power Laser and Particle Beams, Volume. 36, Issue 9, 094004(2024)

High throughput of cell irradiation with microfluidics in single ion microbeam system

Furu Zhan
Author Affiliations
  • Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, China
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    AbstractGet PDF(in Chinese)
    Figures&Tables (6)
    Equations (15)
    References (25)
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    Figures & Tables(6)
    Microfluidic chip with single ion microbeam

    Fig. 1. Microfluidic chip with single ion microbeam

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    irradiation point on the chip

    Fig. 2. irradiation point on the chip

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    Sketch of the ion aiming at the cells

    Fig. 3. Sketch of the ion aiming at the cells

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    Two ions irradiate a cell successively, separation of the two hit points on cell is a, collimator is fixed, b is the beam spot diameter

    Fig. 4. Two ions irradiate a cell successively, separation of the two hit points on cell is a, collimator is fixed, b is the beam spot diameter

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    Number density of the single-row cells in the microfluidic channel

    Fig. 5. Number density of the single-row cells in the microfluidic channel

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    • Table 1. Data of a design example

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      Table 1. Data of a design example

      kd/mmn/s−1m/μL−1vm/(mm·s−1)Qmax /h−1Q/h−1relative error/%
      21.0100025008.530600−−
      21.02000250017.061200 invalid−
      51.0100025003.41224011861−3.1
      51.0200025006.82448023427−4.3
      101.0100025001.761205954−2.7
      101.0200025003.41224011775−3.8
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    Furu Zhan. High throughput of cell irradiation with microfluidics in single ion microbeam system[J]. High Power Laser and Particle Beams, 2024, 36(9): 094004

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    Paper Information

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    Received: Jan. 17, 2024

    Accepted: Jul. 23, 2024

    Published Online: Oct. 15, 2024

    The Author Email:

    DOI:10.11884/HPLPB202436.240023

    Topics

    laser devices and laser physics
    Lasers and Laser Optics
    Laser physics
    laser manufacturing
    Instrumentation, Measurement and Metrology