Acta Optica Sinica, Volume. 40, Issue 4, 430001(2020)
Detection of Cerebral Ischemia Based on Terahertz Time-Domain Spectroscopy
Fig. 1. Schematic diagram of the transmissive terahertz time-domain spectroscopy system
Fig. 2. Results of TTC staining of brain tissues at different ischemia time. (a) 0 h; (b) 2 h; (c) 4 h; (d) 6 h; (e) 24 h
Fig. 3. Preparation of fresh brain ischemic tissue sections
Fig. 4. Terahertz wave properties of the left and right brains of fresh cerebral ischemic tissue at 4 h. (a) Time domain spectrum; (b) frequency domain spectrum; (c) average absorption coefficient; (d) average refractive index
Fig. 5. Relative difference of terahertz wave absorption coefficients between left and right brains in fresh brain tissue at different ischemia time
Fig. 6. Changes in physical properties of brain tissue at different ischemia time. (a) Water content of left and right brains; (b) cell density of left brain
Fig. 7. Preparation of paraffin-embedded cerebral ischemic tissue
Fig. 8. Terahertz wave absorption characteristics of paraffin-embedded cerebral ischemic tissue. (a) Absorption coefficient of left and right brains in paraffin-embedded cerebral ischemic tissue at 4 h; (b) relative difference of terahertz wave absorption coefficients in paraffin-embedded brain tissue between left and right brains at different ischemic time
Fig. 9. Normalized relative difference terahertz wave absorption coefficients between left and right brains and cell density of left brain
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Wang Yuye, Sun Zhongcheng, Xu Degang, Jiang Zhinan, Mu Ning, Yang Chuanyan, Chen Tunan, Feng Hua, Yao Jianquan. Detection of Cerebral Ischemia Based on Terahertz Time-Domain Spectroscopy[J]. Acta Optica Sinica, 2020, 40(4): 430001
Category: Spectroscopy
Received: Oct. 14, 2019
Accepted: --
Published Online: Feb. 11, 2020
The Author Email: Degang Xu (xudegang@tju.edu.cn)