Researching | Serum Metabolomics Study of CCI Model Rats Based on UHPLC-QE-MS

Spectroscopy and Spectral Analysis, Volume. 42, Issue 8, 2528(2022)

Serum Metabolomics Study of CCI Model Rats Based on UHPLC-QE-MS

Feng-yuan BAI1; 2;... Dong-mei ZHAO*, Ren-jun CAI1; 2;, Su-fei SONG1; 2;, Tao LIU1; 2; *; and Qiu-ling XU1; 2; *; |Show fewer author(s)

Author Affiliations

1. The First Affiliated Hospital of Hainan Medical University, Haikou 571199, China

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Figures & Tables(4)

Fig. 1. POS (positive ion mode)

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Fig. 2. NEG (negative ion mode)

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Fig. 3. Bubble diagram of enrichment analysis

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Table 1. Enrichment analysis table

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Table 1. Enrichment analysis table

metabolite set	Total	Hits	P-VALUE	Holm p	FDR
有机酸	914	26	5.60×10^-32	1.51×10^-30	1.51×10^-30
有机杂环化合物	469	17	5.19×10^-23	1.35×10^-21	7.00×10^-22
脂肪酰基	8 120	32	1.38×10^-13	3.46×10^-12	1.24×10^-12
碳水化合物	136	5	1.12×10^-7	2.69×10^-6	7.57×10^-7
核酸	182	5	4.76×10^-7	1.09×10^-5	2.57×10^-6
有机含氮化合物	68	2	0.001 45	0.032	0.006 54
烃类化合物	4	1	0.003 26	0.068 4	0.012 6
有机氧化合物	173	2	0.008 98	0.18	0.030 3
苯类	1 890	5	0.019 9	0.377	0.059 6

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Feng-yuan BAI, Dong-mei ZHAO, Ren-jun CAI, Su-fei SONG, Tao LIU, Qiu-ling XU. Serum Metabolomics Study of CCI Model Rats Based on UHPLC-QE-MS[J]. Spectroscopy and Spectral Analysis, 2022, 42(8): 2528

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Paper Information

Category: Orginal Article

Received: Jul. 9, 2021

Accepted: --

Published Online: Mar. 17, 2025

The Author Email: ZHAO Dong-mei (zhaodongmei@hainmc.edu.cn)

DOI:10.3964/j.issn.1000-0593(2022)08-2528-04

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