Fig. 1. Two-compartmental model of ICG pharmacokinetics

Fig. 2. Schematic of dynamic fluorescence diffuse tomography system

Fig. 3. The simulated reconstruction results of first-order AEKF， second-order AEKF and UKF when the contrast is 2， 3 and 4， and their X-profiles

Fig. 4. Comparison of CNR and QR of the simulation results obtained by first-order AEKF， second-order AEKF and UKF

Fig. 5. Experimental images of mouse liver positioning and scanning， and Micro-CT tomograms of the calibrated parts

Fig. 6. The fusion of the reconstructed images of the time-series fluorescence yield of the mouse liver and the Micro-CT images with the time interval of 4 minutes

Fig. 7. Comparison of the in vivo experimental results of first-order AEKF， second-order AEKF， and UKF

Fig. 8. CNR comparison of K_ep and K_pe obtained by first-order AEKF， second-order EKF and UKF in mouse experiment