Acta Photonica Sinica, Volume. 52, Issue 3, 0352105(2023)

Recent Advances of Photoacoustic Imaging Technology in Biomedicine(Invited)

Xiaowen SHEN, Hongpeng WU, and Lei DONG*
Author Affiliations
  • State Key Laboratory of Quantum Optics and Quantum Optics Devices, Institute of Laser Spectroscopy, Shanxi University, Taiyuan 030006, China
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    Figures & Tables(16)
    Schematic of photoacoustic imaging [21]
    Schematic diagram of photoacoustic computed tomography[27]
    Traditional PACT imaging system with unitary ultrasound transducer[28]
    High-frequency full-field linear array PACT imaging system [29]
    Single-pulse panoramic PACT imaging system[30]
    Different PACT systems for human breast cancer detection[35-36]
    Comparison of OR-PAM and AR-PAM imaging principles[27]
    Diagram of the second generation OR-PAM system designed by WANG L V's group[50]
    Imaging results of the second generation OR-PAM system on the ears of live mice[50]
    Dual-wavelength optical resolution photoacoustic microscopy imaging system[53]
    Schematic diagram of the three-wavelength OR-PAM imaging system[55]
    Imaging of mouse ears under a three-wavelength imaging system[55]
    Schematic diagram of the five-wavelength OR-PAM proposed by Lidai Wang's group [56]
    Results of imaging blood and lymphatic vessels in the mouse ear using five-wavelength OR-PAM[56]
    Schematic diagram of the photoacoustic endoscopic probe [74]
    • Table 1. Comparison of the pros and cons of the three photoacoustic imaging methods

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      Table 1. Comparison of the pros and cons of the three photoacoustic imaging methods

      MethodApplicationResolutionDepthRangeAdditional algorithmsCost
      PACTWide range imaging of small animals or humansLow(hundreds of microns)DeepLargeNeedExpensive
      AR-PAMSubcellular,cellular,and tissue level imagingHighShallowLimited by scanning rangeNo needGeneral
      OR-PAM(hundreds of nanometers -several microns)
      PAEImaging of vascular lining,digestive system,reproductive system

      high

      (more than ten microns)

      ShallowRounded(mostly)No needGeneral
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    Xiaowen SHEN, Hongpeng WU, Lei DONG. Recent Advances of Photoacoustic Imaging Technology in Biomedicine(Invited)[J]. Acta Photonica Sinica, 2023, 52(3): 0352105

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    Paper Information

    Category: Special Issue for Frontiers and Techniques of Laser Spectroscopy

    Received: Jan. 11, 2023

    Accepted: Feb. 8, 2023

    Published Online: Jun. 21, 2023

    The Author Email: DONG Lei (donglei@sxu.edu.cn)

    DOI:10.3788/gzxb20235203.0352105

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