Journal of Radiation Research and Radiation Processing, Volume. 40, Issue 5, 050201(2022)

Study on the degradation characteristics and pathway of torasemide in water via electron beam irradiation

Zhibo ZHANG, Haiyang SHAO*, Lei CHEN, Chengkai MAO, Yingfei REN, and Gang XU
Author Affiliations
  • School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China
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    In this study, electron beam irradiation technology was used to degrade torasemide in an aqueous solution. By investigating the degradation effect, its influencing factors, and degradation products, the radiation degradation characteristics and possible degradation pathways of torasemide were systematically discussed. The study demonstrated that torasemide can be effectively degraded via electron beam irradiation. The experimental results showed that the active •OH particles played a dominant role in the degradation process. The initial torasemide concentration, absorbed dose, pH of the solution, amount of H2O2 and inorganic anions (CO32-,NO2-, SO32-, SO42-) and other environmental factors influence the irradiation effect of torasemide. A higher degradation efficiency was obtained with a lower initial torasemide concentration, higher absorbed dose, and lower pH. The degradation of torasemide was promoted in the presence of SO42- and low concentrations of H2O2, while it was inhibited in the presence of CO32-,NO2-, and SO32-and high concentrations of H2O2. Finally, the degradation products were detected by high performance liquid chromatography-quadrupole time of flight mass spectrometer (HPLC-QTOF), and the degradation pathways were deduced.

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    Zhibo ZHANG, Haiyang SHAO, Lei CHEN, Chengkai MAO, Yingfei REN, Gang XU. Study on the degradation characteristics and pathway of torasemide in water via electron beam irradiation[J]. Journal of Radiation Research and Radiation Processing, 2022, 40(5): 050201

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    Paper Information

    Category: Research Articles

    Received: Feb. 19, 2022

    Accepted: Jun. 28, 2022

    Published Online: Nov. 3, 2022

    The Author Email: SHAO Haiyang (shy2018@shu.edu.cn)

    DOI:10.11889/j.1000-3436.2022-0042

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