Spectroscopy and Spectral Analysis, Volume. 42, Issue 7, 2213(2022)

The Proceedings of Raman Spectroscopy in Cervical Cancer in Recent Five Years

Zhuo-wei SHEN*... Rui LI, Yang WANG, Xiao-guang XU and Zhen XIAO*; |Show fewer author(s)
Author Affiliations
  • The First Affiliated Hopsital of Dalian Medical Unversity, Dalian 116000, China
  • show less
    Figures & Tables(9)
    Classification of Raman technology in cervical cancer research in recent five years
    • Table 1. Raman detection of cervical histology

      View table
      View in Article

      Table 1. Raman detection of cervical histology

      年份样本
      个数
      样本-数据处理方法激发光
      波长/nm
      组织学体内2017[4]26光纤探针-PCA-LDA785
      体外2016[5]61冰冻切片(20 μm)-LDA784.12
      2018[6]245冰冻切片(20 μm)-PC-LDA784.12
      2021[7]210FFPP-SVM532
      2019[8]95FFPP(10 μm)-PCA-SVM532
      2021[9]93FFPP(10 μm)-30种模型532
    • Table 2. Raman comparison of inflammatory tissue and other five tissues

      View table
      View in Article

      Table 2. Raman comparison of inflammatory tissue and other five tissues

      生物分子炎性组织强于炎性组织弱于代表波数/cm-1
      个别脂类、 氨基酸、 胶原和胞嘧啶所有519, 548, 643, 754, 817, 1 369,
      1 506, 1 618
      苯丙氨酸、 酪氨酸和酰胺Ⅰ所有1 002, 1 170, 1 664
      脂质CIN Ⅰ、 CIN Ⅲ、 鳞癌CIN Ⅱ、 腺癌877
      蛋白(α-螺旋)CIN Ⅰ、 CIN Ⅲ、 鳞癌、 腺癌CIN Ⅱ951
      磷脂类CIN Ⅰ、 CIN Ⅱ、 腺癌CIN Ⅲ、 鳞癌1 270
      CH振动CIN Ⅰ、 CIN ⅡCIN Ⅲ、 鳞癌、 腺癌1 449
      色氨酸CIN Ⅰ、 CIN Ⅱ、 鳞癌、 腺癌CIN Ⅲ1 560
    • Table 3. Comparison of biomacromolecules in three tissue samples

      View table
      View in Article

      Table 3. Comparison of biomacromolecules in three tissue samples

      生物分子正常癌前宫颈癌代表波数/cm-1
      DNA最高720, 785, 1 095, 1 258, 1 579
      胶原蛋白存在不存在855, 874, 1 247
      脂质最高1 131, 1 298
      脂肪酸不存在1 300
    • Table 4. Contents of biomacromolecules in three types of cancer tissues

      View table
      View in Article

      Table 4. Contents of biomacromolecules in three types of cancer tissues

      生物分子WDSCCMDSCCPDSCC代表波数/cm-1
      DNA最高1 173, 1 578
      脂质最高1 124
      脂肪酸最高1 300
    • Table 5. Comparison of biomacromolecules in precancerous and cervical cancer samples

      View table
      View in Article

      Table 5. Comparison of biomacromolecules in precancerous and cervical cancer samples

      生物分子癌前宫颈癌代表波数/cm-1
      蛋白质621, 640, 831, 853, 1 001, 1 618
      脂肪酸877, 1 440, 1 656
      DNA/RNA721, 782, 1 084, 1 317, 1 337, 1 575
      磷脂875, 1 032, 1 078, 1 243,
      1 270, 1 330, 1 380
    • Table 6. Raman detection of cervical cytology

      View table
      View in Article

      Table 6. Raman detection of cervical cytology

      年份样本
      个数
      样本-数据处理方法激发光
      波长/nm
      细胞学2018[10]35宫颈脱落细胞-PCA-LDA/PLS-DA532
      2019[11]30宫颈脱落细胞-CARS和SHG显微成像532
      2020[12]96宫颈脱落细胞-Pearson532
      2020[13]-宫颈脱落细胞-PCA-LDA-SVM530
    • Table 7. Hematology Raman detection in diagnosis of cervical lesions

      View table
      View in Article

      Table 7. Hematology Raman detection in diagnosis of cervical lesions

      年份样本
      个数
      样本-数据处理方法激发光
      波长/nm
      血液2020[14]150血清-线性回归方程785
    • Table 8. Wave number of biomacromolecules

      View table
      View in Article

      Table 8. Wave number of biomacromolecules

      代表物质波数/cm-1参考文献代表物质波数/cm-1参考文献
      DNA481, 784, 788, 826[13, 7]半胱氨酸495~516[12]
      DNA/RNA1 320[7]蛋白质951, 1 158, 1 369[7]
      糖类1 370[13]嘧啶环766[7]
      单糖898[12]尿嘧啶780, 784[7, 13]
      二糖898[12]胞嘧啶784, 1 175, 1 290,
      1 506
      [12-13, 7]
      多糖477[7]
      糖原1 025, 1 150[7]胸腺嘧啶784[13]
      葡萄糖-糖带540[13]鸟嘌呤1 175, 1 369[7]
      胶原859, 1 032, 1 303,
      1 309, 1 445
      [12-13, 7]腺嘌呤721[13]
      卟啉1 369[7]
      磷脂酰肌醇415, 519, 576[12, 7]C—C骨架928, 938, 1 130[12-13]
      磷脂1 032, 1 445[12-13, 7]C—C拉伸(胶原蛋白)817[7]
      胆固醇548[7]C—C拉伸(苯丙氨酸)1 339[7]
      胆固醇酯538, 614[12-13, 7]C—H拉伸(蛋白质)1 295[13]
      脂质877, 968, 1 057,
      1 060, 1 095, 1 124,
      1 309, 1 369, 1 437,
      1 452
      [12-13, 7]C—N拉伸(蛋白质)1 053, 1 128[7]
      C—O拉伸(蛋白质)1 053[7]
      核糖振动867, 915[12, 7]
      磷酸化蛋白质和细胞
      核酸的磷酸单酯基团
      970[7]
      丙三醇630[7]
      核酸模式1 340[12-13]磷酸反对称振动1 185~1 300[7]
      酪氨酸640, 642, 643, 830, 835, 853, 855, 859,
      1 170, 1 616
      [12-13, 7]反对称磷酸盐伸缩振动1 230[7]
      酰胺Ⅰ1 637, 1 645, 1 654,
      1 670, 1 697, 1 600~
      1 800, 1 640, 1 655~1 680, 1 664
      [12-13, 7]
      蛋氨酸695[12]
      天冬氨酸1 700~1 750[7]
      谷氨酸1 700~1 750[7]酰胺Ⅲ1 236, 1 243, 1 246,
      1 275
      [12-13, 7]
      色氨酸745, 758, 880, 1 365, 1 560, 1 616, 1 618[12-13, 7]
      A, (DNA碱基中的
      环状呼吸模式)
      1 510[7]
      脯氨酸814, 853, 855, 928,
      1 043
      [12-13, 7]
      CH21 437~1 453, 1 443[7]
      羟脯氨酸1 588[7]类胡萝卜素1 520~1 538[7]
      缬氨酸928[7]
      苯丙氨酸1 000, 1 002, 1 003,
      1 004, 1 030, 1 104,
      1 583, 1 588
      [12-13, 7]
    Tools

    Get Citation

    Copy Citation Text

    Zhuo-wei SHEN, Rui LI, Yang WANG, Xiao-guang XU, Zhen XIAO. The Proceedings of Raman Spectroscopy in Cervical Cancer in Recent Five Years[J]. Spectroscopy and Spectral Analysis, 2022, 42(7): 2213

    Download Citation

    EndNote(RIS)BibTexPlain Text
    Save article for my favorites
    Paper Information

    Category: Orginal Article

    Received: May. 31, 2021

    Accepted: --

    Published Online: Nov. 16, 2022

    The Author Email: SHEN Zhuo-wei (StarrySZW@163.com)

    DOI:10.3964/j.issn.1000-0593(2022)07-2213-05

    Topics