Journal of Innovative Optical Health Sciences, Volume. 7, Issue 5, 1450034(2014)

Deep tissue imaging by enhanced photon collection

Viera Crosignani... Sohail Jahid, Alex, er Dvornikov and Enrico Gratton* |Show fewer author(s)
Author Affiliations
  • Department of Biomedical Engineering University of California at Irvine Irvine, CA 92697-2715, USA
  • show less
    References(21)

    [1] [1] D. O'Malley, "Imaging in depth: Controversies and opportunities," Methods Cell Biol. 89, Ch. 5, 95–128 (2008).

    [2] [2] P. Theer, M. T. Hasan, W. Denk, "Two-photon imaging to a depth of 1000 micron in living brains by use of a Ti:Al2O3 regenerative amplifier," Opt. Lett. 28(12), 1022–1024 (2003).

    [3] [3] D. Kobat, M. E. Durst, N. Nishimura, A. W. Wong, C. B. Schaffer, C. Xu, "Deep tissue multiphoton microscopy using longer wavelength excitation," Opt. Express 17, 13354–13364 (2009).

    [4] [4] R. Cicchi, D. D. Sampson, D. Massi, F. S. Pavone, "Contrast and depth enhancement in two-photon microscopy of human skin ex vivo by use of optical clearing agents," Opt. Express 13, 2337–2344 (2005).

    [5] [5] C. A. Combs, A. V. Smirnov, J. D. Riley, A. H. Gandjbakhche, J. R. Knutson, R. S. Balaban, "Optimization of multiphoton excitation microscopy by total emission detection using a parabolic light reflector," J. Microsc. 228, 330–337 (2007).

    [6] [6] P. J. Campagnola, C. Dong, "Second harmonic generation microscopy: Principles and applications to disease diagnosis," Laser Photon. Rev. 5(1), 13– 26 (2011).

    [7] [7] W. R. Zipfel, R. M. Williams, W. W. Watt, "Nonlinear magic: Multiphoton microscopy in the biosciences," Nat. Biotechnol. 21(11), 1369–1377 (2003).

    [8] [8] X. Chen, C. Raggio, P. J. Campagnola, "Secondharmonic generation circular dichroism studies of osteogenesis imperfecta," Opt Lett. 37, 18 (2012).

    [9] [9] O. Nadiarnykh, R. B. LaComb, M. A. Brewer, P. J. Campagnola, "Alterations of the extracellular matrix in ovarian cancer studied by second harmonic generation imaging microscopy," BMC Cancer 10, 94 (2010).

    [10] [10] V. Ajeti, O. Nadiarnykh, S. M. Ponik, P. J. Keely, K. W. Eliceiri, P. J. Campagnola, "Structural changes in mixed Col I/Col V collagen gels probed by SHG microscopy: Implications for probing stromal alterations in human breast cancer," Biomed. Opt. Express 2(8), 2307–2316 (2011).

    [11] [11] S. V. Plotnikov, A. M. Kenny, S. J. Walsh, B. Zubrowski, C. Joseph, V. L. Scranton, G. A. Kuchel, D. Dauser, M. Xu, C. C. Pilbeam, D. J. Adams, R. P. Dougherty, P. J. Campagnola, W. A. Mohler, "Measurement of muscle disease by quantitative second-harmonic generation imaging," J. Biomed. Opt. 13(4) (2008).

    [12] [12] H. C. Ishikawa-Ankerhold, R. Ankerhold, G. P. C. Drummen, "Advanced fluorescence microscopy techniques — FRAP, FLIP, FLAP, FRET and FLIM," Molecules 17, 4047–4132 (2012).

    [13] [13] P. I. Bastiaens, A. Squire, "Fluorescence lifetime imaging microscopy: Spatial resolution of biochemical processes in the cell," Trends Cell Biol. 9, 48–52 (1999).

    [14] [14] E. B. van Munster, T. W. Gadella, Jr., "Suppression of photobleaching-induced artifacts infrequency-domain FLIM by permutation of the recording order," Cytometry A 58, 185–194 (2004).

    [15] [15] M. A. Digman, V. R. Caiolfa, M. Zamai, E. Gratton, "The phasor approach to fluorescence lifetime imaging analysis," Biophys J. 94(2), L14–L16 (2008).

    [16] [16] V. Crosignani, A. S. Dvornikov, E. Gratton, "Enhancement of imaging depth in turbid media using a wide area detector," J. Biophotonics 4(9), 592–599 (2011).

    [17] [17] V. Crosignani, A. S. Dvornikov, J. S. Aguilar, C. Stringari, R. Edwards, W. W. Mantulin, E. Gratton, "Deep tissue fluorescence imaging and in vivo biological applications," J. Biomed. Opt. 17(11), 116023-1–7 (2012).

    [18] [18] F. Ayers, A. Grant, D. Kuo, D. J. Cuccia, A. J. Durkin, "Fabrication and characterization of silicone- based tissue phantoms with tunable optical properties in the visible and near infrared domain," Proc. SPIE 6870, 687007-1-9 (2008).

    [19] [19] V. Crosignani, A. Dvornikov, E. Gratton "Ultradeep imaging of turbid samples by enhanced photon harvesting," Proc. SPIE 8588, 858810–858811 (2013).

    [20] [20] S. Romani, C. Razzetti, M. Zha, C. Paorici, "Evaluation of the effective second harmonic generation coefficient of monomethyl urea single crystals," Phys. Status Solidi (B) 197, 271 (1996).

    [21] [21] C. Chang, D. Sud, M. Mycek, "Fluorescence lifetime imaging microscopy," Methods Cell Biol. 81, 495– 524 (2007).

    Tools

    Get Citation

    Copy Citation Text

    Viera Crosignani, Sohail Jahid, Alex, er Dvornikov, Enrico Gratton. Deep tissue imaging by enhanced photon collection[J]. Journal of Innovative Optical Health Sciences, 2014, 7(5): 1450034

    Download Citation

    EndNote(RIS)BibTexPlain Text
    Save article for my favorites
    Paper Information

    Received: Jun. 18, 2013

    Accepted: Sep. 16, 2013

    Published Online: Jan. 10, 2019

    The Author Email: Enrico Gratton (egratton@uci.edu)

    DOI:10.1142/s1793545814500345

    Topics