Journal of Innovative Optical Health Sciences, Volume. 7, Issue 5, 1450034(2014)
Deep tissue imaging by enhanced photon collection
[1] [1] D. O'Malley, "Imaging in depth: Controversies and opportunities," Methods Cell Biol. 89, Ch. 5, 95–128 (2008).
[2] [2] P. Theer, M. T. Hasan, W. Denk, "Two-photon imaging to a depth of 1000 micron in living brains by use of a Ti:Al2O3 regenerative amplifier," Opt. Lett. 28(12), 1022–1024 (2003).
[3] [3] D. Kobat, M. E. Durst, N. Nishimura, A. W. Wong, C. B. Schaffer, C. Xu, "Deep tissue multiphoton microscopy using longer wavelength excitation," Opt. Express 17, 13354–13364 (2009).
[4] [4] R. Cicchi, D. D. Sampson, D. Massi, F. S. Pavone, "Contrast and depth enhancement in two-photon microscopy of human skin ex vivo by use of optical clearing agents," Opt. Express 13, 2337–2344 (2005).
[5] [5] C. A. Combs, A. V. Smirnov, J. D. Riley, A. H. Gandjbakhche, J. R. Knutson, R. S. Balaban, "Optimization of multiphoton excitation microscopy by total emission detection using a parabolic light reflector," J. Microsc. 228, 330–337 (2007).
[6] [6] P. J. Campagnola, C. Dong, "Second harmonic generation microscopy: Principles and applications to disease diagnosis," Laser Photon. Rev. 5(1), 13– 26 (2011).
[7] [7] W. R. Zipfel, R. M. Williams, W. W. Watt, "Nonlinear magic: Multiphoton microscopy in the biosciences," Nat. Biotechnol. 21(11), 1369–1377 (2003).
[8] [8] X. Chen, C. Raggio, P. J. Campagnola, "Secondharmonic generation circular dichroism studies of osteogenesis imperfecta," Opt Lett. 37, 18 (2012).
[9] [9] O. Nadiarnykh, R. B. LaComb, M. A. Brewer, P. J. Campagnola, "Alterations of the extracellular matrix in ovarian cancer studied by second harmonic generation imaging microscopy," BMC Cancer 10, 94 (2010).
[10] [10] V. Ajeti, O. Nadiarnykh, S. M. Ponik, P. J. Keely, K. W. Eliceiri, P. J. Campagnola, "Structural changes in mixed Col I/Col V collagen gels probed by SHG microscopy: Implications for probing stromal alterations in human breast cancer," Biomed. Opt. Express 2(8), 2307–2316 (2011).
[11] [11] S. V. Plotnikov, A. M. Kenny, S. J. Walsh, B. Zubrowski, C. Joseph, V. L. Scranton, G. A. Kuchel, D. Dauser, M. Xu, C. C. Pilbeam, D. J. Adams, R. P. Dougherty, P. J. Campagnola, W. A. Mohler, "Measurement of muscle disease by quantitative second-harmonic generation imaging," J. Biomed. Opt. 13(4) (2008).
[12] [12] H. C. Ishikawa-Ankerhold, R. Ankerhold, G. P. C. Drummen, "Advanced fluorescence microscopy techniques — FRAP, FLIP, FLAP, FRET and FLIM," Molecules 17, 4047–4132 (2012).
[13] [13] P. I. Bastiaens, A. Squire, "Fluorescence lifetime imaging microscopy: Spatial resolution of biochemical processes in the cell," Trends Cell Biol. 9, 48–52 (1999).
[14] [14] E. B. van Munster, T. W. Gadella, Jr., "Suppression of photobleaching-induced artifacts infrequency-domain FLIM by permutation of the recording order," Cytometry A 58, 185–194 (2004).
[15] [15] M. A. Digman, V. R. Caiolfa, M. Zamai, E. Gratton, "The phasor approach to fluorescence lifetime imaging analysis," Biophys J. 94(2), L14–L16 (2008).
[16] [16] V. Crosignani, A. S. Dvornikov, E. Gratton, "Enhancement of imaging depth in turbid media using a wide area detector," J. Biophotonics 4(9), 592–599 (2011).
[17] [17] V. Crosignani, A. S. Dvornikov, J. S. Aguilar, C. Stringari, R. Edwards, W. W. Mantulin, E. Gratton, "Deep tissue fluorescence imaging and in vivo biological applications," J. Biomed. Opt. 17(11), 116023-1–7 (2012).
[18] [18] F. Ayers, A. Grant, D. Kuo, D. J. Cuccia, A. J. Durkin, "Fabrication and characterization of silicone- based tissue phantoms with tunable optical properties in the visible and near infrared domain," Proc. SPIE 6870, 687007-1-9 (2008).
[19] [19] V. Crosignani, A. Dvornikov, E. Gratton "Ultradeep imaging of turbid samples by enhanced photon harvesting," Proc. SPIE 8588, 858810–858811 (2013).
[20] [20] S. Romani, C. Razzetti, M. Zha, C. Paorici, "Evaluation of the effective second harmonic generation coefficient of monomethyl urea single crystals," Phys. Status Solidi (B) 197, 271 (1996).
[21] [21] C. Chang, D. Sud, M. Mycek, "Fluorescence lifetime imaging microscopy," Methods Cell Biol. 81, 495– 524 (2007).
Get Citation
Copy Citation Text
Viera Crosignani, Sohail Jahid, Alex, er Dvornikov, Enrico Gratton. Deep tissue imaging by enhanced photon collection[J]. Journal of Innovative Optical Health Sciences, 2014, 7(5): 1450034
Received: Jun. 18, 2013
Accepted: Sep. 16, 2013
Published Online: Jan. 10, 2019
The Author Email: Enrico Gratton (egratton@uci.edu)