[1] HONG Y, FAN H, LI B et al. Fabrication, biological effects, and medical applications of calcium phosphate nanoceramics[J]. Materials Science & Engineering R, 70, 225-242(2010).

[2] DOROZHKIN S V. Calcium orthophosphates in nature[J]. Biology and Medicine Materials, 2, 399-498(2009).

[3] NASIRI-TABRIZI B, HONARMANDI P, EBRAHIMI-KAHRIZSANGI R et al. Synthesis of nanosize single-crystal hydroxyapatite via mechanochemical method[J]. Materials Letters, 63, 543-546(2009).

[4] WANG J, SHAW L L. Nanocrystalline hydroxyapatite with simultaneous enhancements in hardness and toughness[J]. Biomaterials, 30, 6565-6572(2009).

[5] BOSE S, DASGUPTA S, TARAFDER S et al. Microwave-processed nanocrystalline hydroxyapatite: simultaneous enhancement of mechanical and biological properties[J]. Acta Biomater., 6, 3782-3790(2010).

[6] FANG Z, FENG Q, TAN R. In-situ grown hydroxyapatite whiskers reinforced porous HA bioceramic[J]. Ceramics International, 39, 8847-8852(2013).

[7] PROKOPIEV O, SEVOSTIANOV I. Dependence of the mechanical properties of sintered hydroxyapatite on the sintering temperature[J]. Materials Science & Engineering A, 431, 218-227(2006).

[8] HABIBOVIC P, YUAN H, VAN DER VALK C M et al. 3D microenvironment as essential element for osteoinduction by biomaterials[J]. Biomaterials, 26, 3565-3575(2005).

[9] KIM H M, HIMENO T, KOKUBO T et al. Process and kinetics of bonelike apatite formation on sintered hydroxyapatite in a simulated body fluid[J]. Biomaterials, 26, 4366-4373(2005).

[10] RICE R W, WU C C, BOICHELT F. Hardness-grain-size relations in ceramics[J]. Journal of the American Ceramic Society, 77, 2539-2553(1994).

[11] MOSHTAGHIOUN B M, GOMEZ-GARCIA D, DOMINGUEZ- RODRIGUEZ A et al. Grain size dependence of hardness and fracture toughness in pure near fully-dense boron carbide ceramics[J]. Journal of the European Ceramic Society, 36, 1829-1834(2016).

[12] GU Y W, LOH N H, KHOR K A et al. Spark plasma sintering of hydroxyapatite powders[J]. Biomaterials, 23, 37-43(2002).

[13] KIM B N, PRAJATELISTIA E, HAN Y H et al. Transparent hydroxyapatite ceramics consolidated by spark plasma sintering[J]. Scripta Materialia, 69, 366-369(2013).

[14] GUO X, XIAO P, JING L et al. Fabrication of nanostructured hydroxyapatite via hydrothermal synthesis and spark plasma sintering[J]. Journal of the American Ceramic Society, 88, 1026-1029(2005).

[15] RAMESH S, TAN C Y, BHADURI S B et al. Rapid densification of nanocrystalline hydroxyapatite for biomedical applications[J]. Ceramics International, 33, 1363-1367(2007).

[16] VELJOVIC D, JOKIC B, PETROVIĆ R et al. Processing of dense nanostructured HAP ceramics by sintering and hot pressing[J]. Ceramics International, 35, 1407-1413(2009).

[17] WANG J, SHAW L L. Transparent nanocrystalline hydroxyapatite by pressure-assisted sintering[J]. Scripta Materialia, 63, 593-596(2010).

[18] CHEN I W, WANG X H. Sintering dense nanocrystalline ceramics without final-stage grain growth[J]. Nature, 404, 168-171(2000).

[19] LIN K, CHEN L, CHANG J. Fabrication of dense hydroxyapatite nanobioceramics with enhanced mechanical properties via two-step sintering process[J]. International Journal of Applied Ceramic Technology, 9, 479-485(2012).

[20] LUKIĆ M J, ŠKAPIN S D, MARKOVIĆ S et al. Processing route to fully dense nanostructured HAp bioceramics: from powder synthesis to sintering[J]. Journal of the American Ceramic Society, 95, 3394-3402(2012).

[21] THUAULT A, SAVARY E, HORNEZ J C et al. Improvement of the hydroxyapatite mechanical properties by direct microwave sintering in single mode cavity[J]. Journal of the European Ceramic Society, 34, 1865-1871(2014).

[22] LI X, SONG T, CHEN X et al. Osteoinductivity of porous biphasic calcium phosphate ceramic spheres with nanocrystalline and their efficacy in guiding bone regeneration[J]. ACS Applied Materials & Interfaces, 11, 3722-3736(2019).

[23] LIU D, WU Y, WU H et al. Effect of process parameters on the microstructure and property of hydroxyapatite precursor powders and resultant sintered bodies[J]. International Journal of Applied Ceramic Technology, 16, 444-454(2018).

[24] SONG J, YONG L, YING Z et al. Mechanical properties of hydroxyapatite ceramics sintered from powders with different morphologies[J]. Materials Science & Engineering A, 528, 5421-5427(2011).

[25] LANDI E, TAMPIERI A, CELOTTI G et al. Densification behaviour and mechanisms of synthetic hydroxyapatites[J]. Journal of the European Ceramic Society, 20, 2377-2387(2000).

[26] WEINER S, BAR-YOSEF O. States of preservation of bones from prehistoric sites in the Near East: a survey[J]. Journal of Archaeological Science, 17, 187-196(1990).

[27] FARLAY D, PANCZER G, REY C et al. Mineral maturity and crystallinity index are distinct characteristics of bone mineral[J]. Journal of Bone and Mineral Metabolism, 28, 433-445(2010).

[28] LI X, DENG Y, WANG M et al. Stabilization of Ca-deficient hydroxyapatite in biphasic calcium phosphate ceramics by adding alginate to enhance their biological performances[J]. Journal of Materials Chemistry B, 6, 84-97(2017).

[29] MAZAHERI M, HAGHIGHATZADEH M, ZAHEDI A M et al. Effect of a novel sintering process on mechanical properties of hydroxyapatite ceramics[J]. Journal of Alloys & Compounds, 471, 180-184(2009).

[30] DASGUPTA S, TARAFDER S, BANDYOPADHYAY A et al. Effect of grain size on mechanical, surface and biological properties of microwave sintered hydroxyapatite[J]. Materials Science & Engineering C Materials for Biological Applications, 33, 2846-2854(2013).

[31] PANG Y X, BAO X. Influence of temperature, ripening time and calcination on the morphology and crystallinity of hydroxyapatite nanoparticles[J]. Journal of the European Ceramic Society, 23, 1697-1704(2003).

[32] KUMAR R, PRAKASH K, CHEANG P et al. Temperature driven morphological changes of chemically precipitated hydroxyapatite nanoparticles[J]. Langmuir, 20, 5196-5200(2004).

[33] TSENG Y H, KUO C S, LI Y Y et al. Polymer-assisted synthesis of hydroxyapatite nanoparticle[J]. Materials Science and Engineering: C, 29, 819-822(2009).

[34] LI H, XUE F, WAN X et al. Polyethylene glycol-assisted preparation of beta-tricalcium phosphate by direct precipitation method[J]. Powder Technology, 301, 255-260(2016).

[35] AKAO M, AOKI H, KATO K. Mechanical properties of sintered hydroxyapatite for prosthetic applications[J]. Journal of Materials Science, 16, 809-812(1981).

[36] ARIFVIANTO B, MAHARDIKA M, DEWO P et al. Effect of surface mechanical attrition treatment (SMAT) on microhardness, surface roughness and wettability of AISI 316L[J]. Materials Chemistry and Physics, 125, 418-426(2011).

[37] DOS SANTOS E, FARINA M, SOARES G et al. Surface energy of hydroxyapatite and β-tricalcium phosphate ceramics driving serum protein adsorption and osteoblast adhesion[J]. Journal of Materials Science: Materials in Medicine, 19, 2307-2316(2008).

[38] LI B, CHEN X, GUO B et al. Fabrication and cellular biocompatibility of porous carbonated biphasic calcium phosphate ceramics with a nanostructure[J]. Acta Biomaterialia, 5, 134-143(2009).

[39] GUO X, GOUGH J E, XIAO P et al. Fabrication of nanostructured hydroxyapatite and analysis of human osteoblastic cellular response[J]. Journal of Biomedical Materials Research Part A, 82, 1022-1032(2007).

[40] MICHIARDI A, APARICIO C, RATNER B D et al. The influence of surface energy on competitive protein adsorption on oxidized NiTi surfaces[J]. Biomaterials, 28, 586-594(2007).

[41] YAO C, PERLA V, MCKENZIE J L et al. Anodized Ti and Ti₆Al₄V possessing nanometer surface features enhances osteoblast adhesion[J]. Journal of Biomedical Nanotechnology, 1, 68-73(2005).

[42] WEBSTER T J, SIEGEL R W, BIZIOS R. Osteoblast adhesion on nanophase ceramics[J]. Biomaterials, 20, 1221-1227(1999).